Detailed information NTG0671354

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA17_RS04770
• Genome accession: NZ_CP094725
• Coordinates: 1028033..1029076 (+)
• Length: 347 a.a.
• NCBI ID: WP_103207603.1
• Uniprot ID: A0A2K3ZIM8
• Organism: Staphylococcus felis strain IVB6254
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1023033..1034076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA17_RS04745 (MUA17_04750)	-	1024177..1024902 (+)	726	WP_103207595.1	type 1 glutamine amidotransferase	-
MUA17_RS04750 (MUA17_04755)	-	1024982..1025980 (-)	999	WP_115856683.1	aromatic acid exporter family protein	-
MUA17_RS04755 (MUA17_04760)	map	1026077..1026838 (+)	762	WP_115856682.1	type I methionyl aminopeptidase	-
MUA17_RS04760 (MUA17_04765)	-	1026933..1027322 (+)	390	WP_115856681.1	hypothetical protein	-
MUA17_RS04765 (MUA17_04770)	liaF	1027335..1028036 (+)	702	WP_103207601.1	cell wall-active antibiotics response protein LiaF	-
MUA17_RS04770 (MUA17_04775)	vraS	1028033..1029076 (+)	1044	WP_103207603.1	sensor histidine kinase	Regulator
MUA17_RS04775 (MUA17_04780)	vraR	1029066..1029695 (+)	630	WP_103207605.1	response regulator	Regulator
MUA17_RS04780 (MUA17_04785)	-	1029782..1030354 (-)	573	WP_103207607.1	carbonic anhydrase	-
MUA17_RS04785 (MUA17_04790)	-	1030385..1031608 (-)	1224	WP_262633090.1	YihY/virulence factor BrkB family protein	-
MUA17_RS04790 (MUA17_04795)	-	1031971..1032258 (-)	288	WP_103207611.1	YtxH domain-containing protein	-
MUA17_RS04795 (MUA17_04800)	-	1032260..1032724 (-)	465	WP_262633091.1	low molecular weight protein-tyrosine-phosphatase	-
MUA17_RS04800 (MUA17_04805)	-	1032859..1033068 (+)	210	WP_262633092.1	DUF1128 domain-containing protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40184.49 Da
• Isoelectric Point: 5.1680

>NTDB_id=671354 MUA17_RS04770 WP_103207603.1 1028033..1029076(+) (vraS) [Staphylococcus felis strain IVB6254]
MNHYVRTIGSMLILVYSMFTAFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLIVIFLCIIVGSVIAYKINQQNDWLQQ
QIERAFEGETVGVNDQQLELYNETLEIYRSLVPLNQELHKMRIKTQNLTNESYNLNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETNLNPPLDQQIPTLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIRSLVTELQKKVPMKVIQEI
DEFDVPKGIEDHLFRITQEAISNTLRHAKGEQVTVELLKREDYLLLRIQDDGIGFNVDDKIEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEESHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671354 MUA17_RS04770 WP_103207603.1 1028033..1029076(+) (vraS) [Staphylococcus felis strain IVB6254]
ATGAATCACTATGTCAGAACGATTGGGTCAATGCTCATACTAGTTTACAGTATGTTTACAGCTTTCTTTTTTATCGATAA
AGTTTTTGTAAATATCATATTTTTTCAAGGTATGTTTTACACTCAAATCTTCGGTATTCCTGTATTTTTATTTCTTAATT
TAATTGTCATTTTTTTGTGTATTATTGTGGGTAGTGTAATAGCGTATAAGATTAATCAACAAAATGATTGGTTACAACAA
CAGATTGAGCGTGCATTTGAAGGTGAAACGGTCGGTGTTAATGATCAACAACTAGAGCTGTATAATGAAACATTAGAGAT
TTACCGTTCATTGGTACCGCTCAATCAAGAATTACATAAAATGCGAATTAAAACTCAAAATTTGACAAATGAATCTTATA
ACTTAAATGATATAAAAGTAAAAAAAATAATTGAAGATGAACGTCAACGGTTAGCTAGAGAGCTTCACGATAGTGTTTCG
CAGCAATTGTTTGCAGCTAGTATGATGTTATCAGCTATTAAAGAAACAAACTTAAATCCACCACTTGATCAACAGATACC
AACACTTGAAAAAATGATTCAAGACTCACAACTTGAAATGCGAGCATTATTATTACACTTACGTCCAATAGGTTTGAAGG
ATAAATCATTAGGTGAAGGCATACGATCGTTAGTGACTGAATTACAAAAGAAAGTACCTATGAAAGTTATACAAGAAATT
GATGAGTTTGATGTTCCAAAGGGTATAGAAGATCACTTATTTAGAATCACACAAGAGGCAATCTCCAATACGTTACGCCA
TGCTAAGGGTGAACAAGTGACGGTTGAATTGTTAAAAAGAGAAGACTATTTATTATTGCGTATTCAAGATGATGGTATCG
GCTTTAATGTGGACGATAAAATTGAACAAAGTTATGGTTTGAAAAATATGCGTGAAAGAGCAATTGAAATTGGTGCAACT
TTTCATATCGTCTCTTTGCCTGATGCAGGAACACGTATCGAGGTTAAAGCACCATTAGAAAAGGAGGAAAGTCATGACAA
TTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2K3ZIM8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.997	100	0.83