Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA53_RS04405 Genome accession   NZ_CP094724
Coordinates   896761..897390 (+) Length   209 a.a.
NCBI ID   WP_155975539.1    Uniprot ID   -
Organism   Staphylococcus hominis strain IVB6247     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 891761..902390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA53_RS04380 (MUA53_04370) map 892581..893333 (+) 753 WP_002450057.1 type I methionyl aminopeptidase -
  MUA53_RS04385 (MUA53_04375) - 893382..894392 (-) 1011 WP_049432034.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  MUA53_RS04390 (MUA53_04380) - 894620..895006 (+) 387 WP_002450072.1 hypothetical protein -
  MUA53_RS04395 (MUA53_04385) liaF 895027..895728 (+) 702 WP_002450089.1 cell wall-active antibiotics response protein LiaF -
  MUA53_RS04400 (MUA53_04390) vraS 895725..896759 (+) 1035 WP_049415634.1 sensor histidine kinase Regulator
  MUA53_RS04405 (MUA53_04395) vraR 896761..897390 (+) 630 WP_155975539.1 two-component system response regulator VraR Regulator
  MUA53_RS04410 (MUA53_04400) - 897470..898678 (-) 1209 WP_002450069.1 YihY/virulence factor BrkB family protein -
  MUA53_RS04415 (MUA53_04405) - 898770..899051 (-) 282 WP_002450075.1 hypothetical protein -
  MUA53_RS04420 (MUA53_04410) - 899057..899521 (-) 465 WP_049335620.1 low molecular weight protein-tyrosine-phosphatase -
  MUA53_RS04425 (MUA53_04415) - 899663..899869 (+) 207 WP_002450082.1 DUF1128 domain-containing protein -
  MUA53_RS04430 (MUA53_04420) - 899881..901128 (+) 1248 WP_155975540.1 aminopeptidase -
  MUA53_RS04435 (MUA53_04425) - 901161..901694 (+) 534 WP_002488082.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23606.29 Da        Isoelectric Point: 5.3673

>NTDB_id=671323 MUA53_RS04405 WP_155975539.1 896761..897390(+) (vraR) [Staphylococcus hominis strain IVB6247]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLIKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=671323 MUA53_RS04405 WP_155975539.1 896761..897390(+) (vraR) [Staphylococcus hominis strain IVB6247]
ATGACGATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGGGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCACATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGGGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCAAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCAGTATTTGAGCCAGAAGTTTTAATAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.258

100

0.943
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378