Detailed information NTG0671322

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA53_RS04400
• Genome accession: NZ_CP094724
• Coordinates: 895725..896759 (+)
• Length: 344 a.a.
• NCBI ID: WP_049415634.1
• Uniprot ID: A0A974KWJ9
• Organism: Staphylococcus hominis strain IVB6247
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 890725..901759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA53_RS04375 (MUA53_04365)	-	891418..892407 (-)	990	WP_115344796.1	aromatic acid exporter family protein	-
MUA53_RS04380 (MUA53_04370)	map	892581..893333 (+)	753	WP_002450057.1	type I methionyl aminopeptidase	-
MUA53_RS04385 (MUA53_04375)	-	893382..894392 (-)	1011	WP_049432034.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
MUA53_RS04390 (MUA53_04380)	-	894620..895006 (+)	387	WP_002450072.1	hypothetical protein	-
MUA53_RS04395 (MUA53_04385)	liaF	895027..895728 (+)	702	WP_002450089.1	cell wall-active antibiotics response protein LiaF	-
MUA53_RS04400 (MUA53_04390)	vraS	895725..896759 (+)	1035	WP_049415634.1	sensor histidine kinase	Regulator
MUA53_RS04405 (MUA53_04395)	vraR	896761..897390 (+)	630	WP_155975539.1	two-component system response regulator VraR	Regulator
MUA53_RS04410 (MUA53_04400)	-	897470..898678 (-)	1209	WP_002450069.1	YihY/virulence factor BrkB family protein	-
MUA53_RS04415 (MUA53_04405)	-	898770..899051 (-)	282	WP_002450075.1	hypothetical protein	-
MUA53_RS04420 (MUA53_04410)	-	899057..899521 (-)	465	WP_049335620.1	low molecular weight protein-tyrosine-phosphatase	-
MUA53_RS04425 (MUA53_04415)	-	899663..899869 (+)	207	WP_002450082.1	DUF1128 domain-containing protein	-
MUA53_RS04430 (MUA53_04420)	-	899881..901128 (+)	1248	WP_155975540.1	aminopeptidase	-
MUA53_RS04435 (MUA53_04425)	-	901161..901694 (+)	534	WP_002488082.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39629.22 Da
• Isoelectric Point: 6.3137

>NTDB_id=671322 MUA53_RS04400 WP_049415634.1 895725..896759(+) (vraS) [Staphylococcus hominis strain IVB6247]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSVLAYKINQQNDWIKN
QIEHAIEGETVGINDKNIELYNETIDIYQMLVPLNQELQKLRIKTQNLTNENYNMNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELAPPLNQQIPVLEKMIQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIYDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNHQDYLLLRIQDNGKGFNVDEKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLTKEEG

Nucleotide

• Length: 1035 bp

>NTDB_id=671322 MUA53_RS04400 WP_049415634.1 895725..896759(+) (vraS) [Staphylococcus hominis strain IVB6247]
ATGAATCACTATTTAAGAGCAATAGGATCCATGCTTATTTTAGTGTATAGCATGCTAACTGCGTTTTTATTTATAGATAA
AGTTTTTGTAAATATTATATATTTTCAAGGAATGTTCTATACTCAAATATTTGGTATACCTGTGTTTCTATTTCTTAATT
TAGTGATTATTTTACTTTGTATTATCGTTGGCTCTGTATTAGCTTATAAAATAAATCAGCAAAATGATTGGATAAAGAAT
CAAATTGAACATGCCATTGAAGGTGAAACGGTAGGGATTAATGATAAAAACATAGAACTATATAATGAGACGATTGATAT
TTATCAAATGTTAGTGCCTTTAAATCAAGAATTACAGAAATTAAGAATTAAAACTCAAAATTTAACAAATGAAAACTATA
ATATGAATGACATTAAAGTTAAAAAAATCATAGAAGATGAGCGTCAGCGTTTAGCAAGGGAACTACACGATTCAGTAAGT
CAACAACTTTTCGCAGCAAGTATGATGCTATCAGCGATAAAAGAAACAGAACTAGCACCACCTCTTAATCAACAAATTCC
AGTACTTGAGAAAATGATACAAGAATCTCAATTAGAGATGCGAGCGCTATTACTACATTTGCGACCTTTAGGACTCAAAG
ATAAATCATTAGGGGAAGGTATTAAAGATTTAGTCATTGATTTACAAAAGAAAGTACCTATGAAAGTCATTTATGATATA
CAAGATTTTAAAGTTCCTAAAGGAATTGAAGATCATCTATTTCGAATTACACAAGAGGCAATTTCAAATACATTAAGACA
TTCTAATGGAACTAAAGTGACAGTAGAATTATTTAATCATCAAGATTATTTATTATTAAGAATTCAGGATAATGGTAAAG
GTTTTAACGTAGATGAAAAAGTAGAACAAAGTTATGGATTGAAAAATATGAGAGAACGTGCATTAGAAATAGGTGCAACG
TTTCATATCGTATCTTTACCAGATTCAGGAACTAGAATAGAGGTAAAAGCACCTTTAACGAAAGAGGAGGGTTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	90.116	100	0.901