Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA82_RS04965 Genome accession   NZ_CP094709
Coordinates   1086695..1087324 (+) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6174     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1081695..1092324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA82_RS04940 (MUA82_04945) - 1082467..1083453 (-) 987 WP_002481667.1 aromatic acid exporter family protein -
  MUA82_RS04945 (MUA82_04950) map 1083673..1084437 (+) 765 WP_107587638.1 type I methionyl aminopeptidase -
  MUA82_RS04950 (MUA82_04955) - 1084553..1084948 (+) 396 WP_002481665.1 hypothetical protein -
  MUA82_RS04955 (MUA82_04960) liaF 1084964..1085665 (+) 702 WP_002481664.1 cell wall-active antibiotics response protein LiaF -
  MUA82_RS04960 (MUA82_04965) vraS 1085662..1086705 (+) 1044 WP_002481663.1 sensor histidine kinase Regulator
  MUA82_RS04965 (MUA82_04970) vraR 1086695..1087324 (+) 630 WP_002481662.1 response regulator transcription factor Regulator
  MUA82_RS04970 (MUA82_04975) - 1087395..1087973 (-) 579 WP_002481661.1 carbonic anhydrase -
  MUA82_RS04975 (MUA82_04980) - 1088181..1089257 (-) 1077 WP_002481660.1 YihY/virulence factor BrkB family protein -
  MUA82_RS04980 (MUA82_04985) - 1089388..1089678 (-) 291 WP_002481659.1 hypothetical protein -
  MUA82_RS04985 (MUA82_04990) - 1089686..1090150 (-) 465 WP_023015860.1 low molecular weight protein-tyrosine-phosphatase -
  MUA82_RS04990 (MUA82_04995) - 1090374..1090580 (+) 207 WP_002481657.1 DUF1128 family protein -
  MUA82_RS04995 (MUA82_05000) - 1090617..1091855 (+) 1239 WP_023015859.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=670900 MUA82_RS04965 WP_002481662.1 1086695..1087324(+) (vraR) [Staphylococcus simulans strain IVB6174]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=670900 MUA82_RS04965 WP_002481662.1 1086695..1087324(+) (vraR) [Staphylococcus simulans strain IVB6174]
ATGGCGATTAAAGTATTATTTGTCGATGACCACGAAATGGTTCGTATCGGCATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCTCATGAATTGCAGCCTGATTTAATCTTGA
TGGATTTGTTGATGGAAGACATGGATGGCGTAGAAGCTACAATGCAGATTAAAAAAGATTTACCTCAGATTAAAGTATTG
ATGCTGACAAGTTATATTGAGGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGACAGTTATATTCTAAAAACGAC
GAGCGCAAGTGATATCGCAGAAGCGATTCGTAAAACATATCGTAACGAAGCGGTGTTTGAAGCGGAAGTACTTGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAATTATATGAATTATTAACAGATAGAGAAATGGAAATTTTATTGTTAATCGCA
AAAGGTTATTCTAACCAAGAAATCGCTAGTGCGTCACATATTACGATTAAAACAGTTAAAACACATGTGAGTAATATATT
GAGCAAGCTAGAAGTTCAAGACAGAACACAAGCTGTTATTTACGCATTCCAACATGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368