Detailed information NTG0670899

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA82_RS04960
• Genome accession: NZ_CP094709
• Coordinates: 1085662..1086705 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6174
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1080662..1091705

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA82_RS04935 (MUA82_04940)	-	1081665..1082384 (+)	720	WP_262583305.1	type 1 glutamine amidotransferase	-
MUA82_RS04940 (MUA82_04945)	-	1082467..1083453 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA82_RS04945 (MUA82_04950)	map	1083673..1084437 (+)	765	WP_107587638.1	type I methionyl aminopeptidase	-
MUA82_RS04950 (MUA82_04955)	-	1084553..1084948 (+)	396	WP_002481665.1	hypothetical protein	-
MUA82_RS04955 (MUA82_04960)	liaF	1084964..1085665 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA82_RS04960 (MUA82_04965)	vraS	1085662..1086705 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA82_RS04965 (MUA82_04970)	vraR	1086695..1087324 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA82_RS04970 (MUA82_04975)	-	1087395..1087973 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA82_RS04975 (MUA82_04980)	-	1088181..1089257 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
MUA82_RS04980 (MUA82_04985)	-	1089388..1089678 (-)	291	WP_002481659.1	hypothetical protein	-
MUA82_RS04985 (MUA82_04990)	-	1089686..1090150 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA82_RS04990 (MUA82_04995)	-	1090374..1090580 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670899 MUA82_RS04960 WP_002481663.1 1085662..1086705(+) (vraS) [Staphylococcus simulans strain IVB6174]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670899 MUA82_RS04960 WP_002481663.1 1085662..1086705(+) (vraS) [Staphylococcus simulans strain IVB6174]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAGTTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCAGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862