Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA81_RS05170 Genome accession   NZ_CP094697
Coordinates   1108312..1108941 (+) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6244     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1103312..1113941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA81_RS05145 (MUA81_05135) - 1104084..1105070 (-) 987 WP_002481667.1 aromatic acid exporter family protein -
  MUA81_RS05150 (MUA81_05140) map 1105290..1106054 (+) 765 WP_262901254.1 type I methionyl aminopeptidase -
  MUA81_RS05155 (MUA81_05145) - 1106170..1106565 (+) 396 WP_002481665.1 hypothetical protein -
  MUA81_RS05160 (MUA81_05150) liaF 1106581..1107282 (+) 702 WP_002481664.1 cell wall-active antibiotics response protein LiaF -
  MUA81_RS05165 (MUA81_05155) vraS 1107279..1108322 (+) 1044 WP_262901255.1 sensor histidine kinase Regulator
  MUA81_RS05170 (MUA81_05160) vraR 1108312..1108941 (+) 630 WP_002481662.1 response regulator transcription factor Regulator
  MUA81_RS05175 (MUA81_05165) - 1109012..1109590 (-) 579 WP_002481661.1 carbonic anhydrase -
  MUA81_RS05180 (MUA81_05170) - 1109798..1110874 (-) 1077 WP_262901256.1 YihY/virulence factor BrkB family protein -
  MUA81_RS05185 (MUA81_05175) - 1111005..1111295 (-) 291 WP_002481659.1 hypothetical protein -
  MUA81_RS05190 (MUA81_05180) - 1111303..1111767 (-) 465 WP_023015860.1 low molecular weight protein-tyrosine-phosphatase -
  MUA81_RS05195 (MUA81_05185) - 1111991..1112197 (+) 207 WP_002481657.1 DUF1128 family protein -
  MUA81_RS05200 (MUA81_05190) - 1112234..1113472 (+) 1239 WP_107547749.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=670720 MUA81_RS05170 WP_002481662.1 1108312..1108941(+) (vraR) [Staphylococcus simulans strain IVB6244]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=670720 MUA81_RS05170 WP_002481662.1 1108312..1108941(+) (vraR) [Staphylococcus simulans strain IVB6244]
ATGGCGATTAAAGTATTATTTGTCGATGACCACGAAATGGTTCGTATCGGCATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCTCATGAATTGCAGCCTGATTTAATCTTGA
TGGATTTGTTGATGGAAGACATGGATGGCGTAGAAGCTACAATGCAGATTAAAAAAGATTTACCTCAGATTAAAGTATTG
ATGCTGACAAGTTATATTGAGGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGACAGTTATATTCTAAAAACGAC
GAGCGCAAGTGATATCGCAGAAGCGATTCGTAAAACATATCGTAACGAAGCGGTGTTTGAAGCGGAAGTACTTGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAATTATATGAATTATTAACAGATAGAGAAATGGAAATTTTATTGTTAATCGCA
AAAGGTTATTCTAACCAAGAAATCGCCAGTGCGTCACATATTACGATTAAAACAGTTAAAACACATGTGAGTAATATATT
AAGCAAGCTAGAAGTTCAAGACAGAACACAAGCTGTTATTTACGCATTCCAACACGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368