Detailed information NTG0670719

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA81_RS05165
• Genome accession: NZ_CP094697
• Coordinates: 1107279..1108322 (+)
• Length: 347 a.a.
• NCBI ID: WP_262901255.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6244
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1102279..1113322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA81_RS05140 (MUA81_05130)	-	1103282..1104001 (+)	720	WP_023015863.1	type 1 glutamine amidotransferase	-
MUA81_RS05145 (MUA81_05135)	-	1104084..1105070 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA81_RS05150 (MUA81_05140)	map	1105290..1106054 (+)	765	WP_262901254.1	type I methionyl aminopeptidase	-
MUA81_RS05155 (MUA81_05145)	-	1106170..1106565 (+)	396	WP_002481665.1	hypothetical protein	-
MUA81_RS05160 (MUA81_05150)	liaF	1106581..1107282 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA81_RS05165 (MUA81_05155)	vraS	1107279..1108322 (+)	1044	WP_262901255.1	sensor histidine kinase	Regulator
MUA81_RS05170 (MUA81_05160)	vraR	1108312..1108941 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA81_RS05175 (MUA81_05165)	-	1109012..1109590 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA81_RS05180 (MUA81_05170)	-	1109798..1110874 (-)	1077	WP_262901256.1	YihY/virulence factor BrkB family protein	-
MUA81_RS05185 (MUA81_05175)	-	1111005..1111295 (-)	291	WP_002481659.1	hypothetical protein	-
MUA81_RS05190 (MUA81_05180)	-	1111303..1111767 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA81_RS05195 (MUA81_05185)	-	1111991..1112197 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39931.17 Da
• Isoelectric Point: 4.8944

>NTDB_id=670719 MUA81_RS05165 WP_262901255.1 1107279..1108322(+) (vraS) [Staphylococcus simulans strain IVB6244]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDFTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670719 MUA81_RS05165 WP_262901255.1 1107279..1108322(+) (vraS) [Staphylococcus simulans strain IVB6244]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATTTTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATCGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTCACCAATGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTATTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	85.879	100	0.859