Detailed information NTG0668084

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MP387_RS01125
• Genome accession: NZ_CP094226
• Coordinates: 215264..216274 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis strain 1648
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 210264..221274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MP387_RS01100 (MP387_01100)	-	210577..211899 (+)	1323	WP_242747046.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
MP387_RS01105 (MP387_01105)	folE	211880..212434 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
MP387_RS01110 (MP387_01110)	folK	212594..213415 (+)	822	WP_242747048.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
MP387_RS01115 (MP387_01115)	-	213408..214691 (+)	1284	WP_242747050.1	DUF308 domain-containing protein	-
MP387_RS01120 (MP387_01120)	-	214742..215059 (-)	318	WP_242747052.1	DUF960 domain-containing protein	-
MP387_RS01125 (MP387_01125)	ccpA	215264..216274 (+)	1011	WP_001090635.1	catabolite control protein A	Regulator
MP387_RS01130 (MP387_01130)	-	216327..217289 (-)	963	WP_242747054.1	asparaginase	-
MP387_RS01135 (MP387_01135)	-	217355..218746 (+)	1392	WP_242747057.1	Cof-type HAD-IIB family hydrolase	-
MP387_RS01140 (MP387_01140)	-	219239..221215 (+)	1977	WP_242747059.1	CAP domain-containing protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=668084 MP387_RS01125 WP_001090635.1 215264..216274(+) (ccpA) [Streptococcus oralis strain 1648]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=668084 MP387_RS01125 WP_001090635.1 215264..216274(+) (ccpA) [Streptococcus oralis strain 1648]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCGATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTATCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTAATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGTGAGGGATTGGTCTTTGAATCAAAATACAGCTATGACGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTGTTGAATGGTTTAGCTGACCATGGTGTATCTGTACC
GGAAGAGTTTGAAATCATCACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTGCCTCATGGTTTGACAGAGCGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568