Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG43_RS00710 Genome accession   NZ_CP094175
Coordinates   151885..152628 (+) Length   247 a.a.
NCBI ID   WP_245030615.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe063     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146885..157628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG43_RS00685 (MPG43_00685) panD 149037..149387 (+) 351 WP_000142212.1 aspartate 1-decarboxylase -
  MPG43_RS00690 (MPG43_00690) - 149398..149691 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  MPG43_RS00695 (MPG43_00695) - 149691..150686 (+) 996 WP_245031212.1 PDZ domain-containing protein -
  MPG43_RS00700 (MPG43_00700) comB6 150692..151747 (+) 1056 WP_245031213.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG43_RS00705 (MPG43_00705) comB7 151763..151888 (+) 126 WP_001217874.1 hypothetical protein Machinery gene
  MPG43_RS00710 (MPG43_00710) comB8 151885..152628 (+) 744 WP_245030615.1 virB8 family protein Machinery gene
  MPG43_RS00715 (MPG43_00715) comB9 152628..153593 (+) 966 WP_245030617.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG43_RS00720 (MPG43_00720) comB10 153586..154722 (+) 1137 WP_245030629.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG43_RS00725 (MPG43_00725) - 154792..156204 (+) 1413 WP_245030631.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG43_RS00730 (MPG43_00730) gmd 156219..157364 (+) 1146 WP_245030633.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28731.97 Da        Isoelectric Point: 9.2662

>NTDB_id=668011 MPG43_RS00710 WP_245030615.1 151885..152628(+) (comB8) [Helicobacter pylori strain Hpfe063]
MKERPFNSEQLIYLEELLSHQEKRLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=668011 MPG43_RS00710 WP_245030615.1 151885..152628(+) (comB8) [Helicobacter pylori strain Hpfe063]
ATGAAAGAAAGGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCGTTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAAGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.964

Multiple sequence alignment