Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG04_RS00720 Genome accession   NZ_CP094161
Coordinates   149458..150201 (+) Length   247 a.a.
NCBI ID   WP_000660524.1    Uniprot ID   A0AAI8F143
Organism   Helicobacter pylori strain Hpfe0015     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 144458..155201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG04_RS00695 (MPG04_00695) panD 146610..146960 (+) 351 WP_245044529.1 aspartate 1-decarboxylase -
  MPG04_RS00700 (MPG04_00700) - 146971..147264 (+) 294 WP_131128566.1 YbaB/EbfC family nucleoid-associated protein -
  MPG04_RS00705 (MPG04_00705) - 147264..148259 (+) 996 WP_245044999.1 PDZ domain-containing protein -
  MPG04_RS00710 (MPG04_00710) comB6 148265..149320 (+) 1056 WP_245044530.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG04_RS00715 (MPG04_00715) comB7 149336..149461 (+) 126 WP_001217874.1 hypothetical protein Machinery gene
  MPG04_RS00720 (MPG04_00720) comB8 149458..150201 (+) 744 WP_000660524.1 virB8 family protein Machinery gene
  MPG04_RS00725 (MPG04_00725) comB9 150201..151163 (+) 963 WP_245044532.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG04_RS00730 (MPG04_00730) comB10 151156..152292 (+) 1137 WP_245044533.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG04_RS00735 (MPG04_00735) - 152363..153778 (+) 1416 WP_245044534.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG04_RS00740 (MPG04_00740) gmd 153789..154934 (+) 1146 WP_245044535.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=667812 MPG04_RS00720 WP_000660524.1 149458..150201(+) (comB8) [Helicobacter pylori strain Hpfe0015]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667812 MPG04_RS00720 WP_000660524.1 149458..150201(+) (comB8) [Helicobacter pylori strain Hpfe0015]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCATCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment