Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG52_RS00970 Genome accession   NZ_CP094157
Coordinates   206347..207090 (+) Length   247 a.a.
NCBI ID   WP_180598095.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0021     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 201347..212090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG52_RS00945 (MPG52_00945) panD 203505..203858 (+) 354 WP_079357806.1 aspartate 1-decarboxylase -
  MPG52_RS00950 (MPG52_00950) - 203861..204163 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  MPG52_RS00955 (MPG52_00955) - 204163..205158 (+) 996 WP_245077217.1 PDZ domain-containing protein -
  MPG52_RS00960 (MPG52_00960) comB6 205166..206221 (+) 1056 WP_245077218.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG52_RS00965 (MPG52_00965) comB7 206237..206350 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  MPG52_RS00970 (MPG52_00970) comB8 206347..207090 (+) 744 WP_180598095.1 virB8 family protein Machinery gene
  MPG52_RS00975 (MPG52_00975) comB9 207090..208073 (+) 984 WP_180598092.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG52_RS00980 (MPG52_00980) comB10 208066..209196 (+) 1131 WP_245076829.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG52_RS00985 (MPG52_00985) - 209266..210678 (+) 1413 WP_245076831.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG52_RS00990 (MPG52_00990) gmd 210718..211863 (+) 1146 WP_245076833.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28666.88 Da        Isoelectric Point: 8.9830

>NTDB_id=667754 MPG52_RS00970 WP_180598095.1 206347..207090(+) (comB8) [Helicobacter pylori strain Hpfe0021]
MKEKPFNSEQLVFLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667754 MPG52_RS00970 WP_180598095.1 206347..207090(+) (comB8) [Helicobacter pylori strain Hpfe0021]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTAGTCTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAACGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGCATTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGCTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGACTTAATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTAACGAACGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTAAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment