Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG81_RS00725 Genome accession   NZ_CP094151
Coordinates   156262..157005 (+) Length   247 a.a.
NCBI ID   WP_245087269.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe019     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 151262..162005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG81_RS00700 (MPG81_00700) panD 153414..153764 (+) 351 WP_245087265.1 aspartate 1-decarboxylase -
  MPG81_RS00705 (MPG81_00705) - 153775..154068 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  MPG81_RS00710 (MPG81_00710) - 154068..155063 (+) 996 WP_245088312.1 PDZ domain-containing protein -
  MPG81_RS00715 (MPG81_00715) comB6 155069..156124 (+) 1056 WP_180589278.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG81_RS00720 (MPG81_00720) comB7 156140..156265 (+) 126 WP_001217874.1 hypothetical protein Machinery gene
  MPG81_RS00725 (MPG81_00725) comB8 156262..157005 (+) 744 WP_245087269.1 virB8 family protein Machinery gene
  MPG81_RS00730 (MPG81_00730) comB9 157005..157967 (+) 963 WP_245087272.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG81_RS00735 (MPG81_00735) comB10 157960..159096 (+) 1137 WP_245087274.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG81_RS00740 (MPG81_00740) - 159166..160578 (+) 1413 WP_245087277.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG81_RS00745 (MPG81_00745) gmd 160592..161737 (+) 1146 WP_245087280.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28613.83 Da        Isoelectric Point: 8.9546

>NTDB_id=667681 MPG81_RS00725 WP_245087269.1 156262..157005(+) (comB8) [Helicobacter pylori strain Hpfe019]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAVVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSGSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667681 MPG81_RS00725 WP_245087269.1 156262..157005(+) (comB8) [Helicobacter pylori strain Hpfe019]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGGTTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAACATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCGGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment