Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG13_RS00710 Genome accession   NZ_CP094137
Coordinates   148476..149219 (+) Length   247 a.a.
NCBI ID   WP_000660524.1    Uniprot ID   A0AAI8F143
Organism   Helicobacter pylori strain Hpfe038     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 143476..154219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG13_RS00685 (MPG13_00685) panD 145628..145978 (+) 351 WP_180602206.1 aspartate 1-decarboxylase -
  MPG13_RS00690 (MPG13_00690) - 145989..146282 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  MPG13_RS00695 (MPG13_00695) - 146282..147277 (+) 996 WP_180602221.1 PDZ domain-containing protein -
  MPG13_RS00700 (MPG13_00700) comB6 147283..148338 (+) 1056 WP_245083569.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG13_RS00705 (MPG13_00705) comB7 148354..148479 (+) 126 WP_180508795.1 comB7 lipoprotein Machinery gene
  MPG13_RS00710 (MPG13_00710) comB8 148476..149219 (+) 744 WP_000660524.1 virB8 family protein Machinery gene
  MPG13_RS00715 (MPG13_00715) comB9 149219..150181 (+) 963 WP_180602210.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG13_RS00720 (MPG13_00720) comB10 150174..151310 (+) 1137 WP_245083571.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG13_RS00725 (MPG13_00725) - 151380..152792 (+) 1413 WP_245083578.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG13_RS00730 (MPG13_00730) gmd 152806..153951 (+) 1146 WP_220835406.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=667427 MPG13_RS00710 WP_000660524.1 148476..149219(+) (comB8) [Helicobacter pylori strain Hpfe038]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667427 MPG13_RS00710 WP_000660524.1 148476..149219(+) (comB8) [Helicobacter pylori strain Hpfe038]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCGCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGAGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment