Detailed information NTG0066627

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: IOMTU433_RS04305
• Genome accession: NZ_AP014649
• Coordinates: 928524..930956 (+)
• Length: 810 a.a.
• NCBI ID: WP_032037654.1
• Uniprot ID: A0A1Y1P441
• Organism: Acinetobacter baumannii strain IOMTU433
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 923524..935956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IOMTU433_RS04280 (IOMTU433_0866)	-	923675..924616 (-)	942	WP_000795874.1	hypothetical protein	-
IOMTU433_RS04285 (IOMTU433_0867)	-	924873..925358 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
IOMTU433_RS04290 (IOMTU433_0868)	-	925369..926277 (+)	909	WP_001140078.1	EamA family transporter	-
IOMTU433_RS21130	-	926307..926505 (-)	199	Protein_826	hypothetical protein	-
IOMTU433_RS04295 (IOMTU433_0869)	-	926525..927760 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
IOMTU433_RS04300 (IOMTU433_0870)	lolD	927753..928439 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
IOMTU433_RS04305 (IOMTU433_0871)	comA/comEC	928524..930956 (+)	2433	WP_032037654.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
IOMTU433_RS04310 (IOMTU433_0872)	-	930909..931892 (-)	984	WP_086222346.1	lysophospholipid acyltransferase family protein	-
IOMTU433_RS04315 (IOMTU433_0873)	sppA	932029..933045 (+)	1017	WP_001286612.1	signal peptide peptidase SppA	-
IOMTU433_RS04320 (IOMTU433_0874)	-	933064..933873 (+)	810	WP_045543784.1	alpha/beta hydrolase	-
IOMTU433_RS04325 (IOMTU433_0875)	purN	933936..934565 (-)	630	WP_000975534.1	phosphoribosylglycinamide formyltransferase	-
IOMTU433_RS04330 (IOMTU433_0876)	purM	934562..935632 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92494.91 Da
• Isoelectric Point: 8.6716

>NTDB_id=66627 IOMTU433_RS04305 WP_032037654.1 928524..930956(+) (comA/comEC) [Acinetobacter baumannii strain IOMTU433]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTISLFMVGYYYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQHHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQILMAVPCCLGVLIYTA
FVGFEIPALRTLLSVFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLTLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQKWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=66627 IOMTU433_RS04305 WP_032037654.1 928524..930956(+) (comA/comEC) [Acinetobacter baumannii strain IOMTU433]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCTATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAATAAGTCTTTTTATGGTTGGTTACTACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTCTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCACCATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATTAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGATTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGTATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTAACATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATTATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGGCAGGGGCAG
GCCATTTTTTTACAACATTCCGAACAAAAATGGTTAATTGACACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTAGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAACCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-522)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

3D structure

• AlphaFold DB: A0A1Y1P441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.395	100	0.984
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504