Detailed information
Bioinformatically predicted
Overview
| Name | ccpA | Type | Regulator |
| Locus tag | SCSC_RS05345 | Genome accession | NZ_AP014647 |
| Coordinates | 1079008..1080012 (-) | Length | 334 a.a. |
| NCBI ID | WP_006270669.1 | Uniprot ID | A0AAD2Y396 |
| Organism | Streptococcus constellatus subsp. constellatus strain CCUG 24889 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1072610..1167109 | 1079008..1080012 | within | 0 |
Gene organization within MGE regions
Location: 1072610..1167109
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SCSC_RS05310 | - | 1072745..1073058 (-) | 314 | Protein_1029 | YbaN family protein | - |
| SCSC_RS05315 (SCSC_1098) | vicX | 1073092..1073895 (-) | 804 | WP_006270665.1 | MBL fold metallo-hydrolase | Regulator |
| SCSC_RS05320 (SCSC_1099) | micB | 1073897..1075249 (-) | 1353 | WP_006270686.1 | cell wall metabolism sensor histidine kinase VicK | Regulator |
| SCSC_RS05325 (SCSC_1100) | micA | 1075242..1075943 (-) | 702 | WP_003035055.1 | response regulator YycF | Regulator |
| SCSC_RS05330 (SCSC_1101) | - | 1076244..1076576 (-) | 333 | WP_006268722.1 | hypothetical protein | - |
| SCSC_RS05335 (SCSC_1102) | - | 1076603..1077916 (-) | 1314 | WP_006268747.1 | glycosyltransferase family 4 protein | - |
| SCSC_RS05340 (SCSC_1103) | - | 1077918..1078916 (-) | 999 | WP_003068685.1 | glycosyltransferase | - |
| SCSC_RS05345 (SCSC_1104) | ccpA | 1079008..1080012 (-) | 1005 | WP_006270669.1 | catabolite control protein A | Regulator |
| SCSC_RS05350 (SCSC_1105) | - | 1080277..1081359 (+) | 1083 | WP_006270659.1 | Xaa-Pro peptidase family protein | - |
| SCSC_RS05355 (SCSC_1106) | - | 1081882..1082463 (-) | 582 | WP_006270715.1 | class I SAM-dependent methyltransferase | - |
| SCSC_RS05360 (SCSC_1107) | galE | 1082722..1083741 (-) | 1020 | WP_006270663.1 | UDP-glucose 4-epimerase GalE | - |
| SCSC_RS05365 (SCSC_1108) | rfbB | 1083776..1084822 (-) | 1047 | WP_006270678.1 | dTDP-glucose 4,6-dehydratase | - |
| SCSC_RS05370 (SCSC_1109) | - | 1084854..1085447 (-) | 594 | WP_006270667.1 | dTDP-4-dehydrorhamnose 3,5-epimerase family protein | - |
| SCSC_RS05375 (SCSC_1110) | rfbA | 1085451..1086320 (-) | 870 | WP_006268635.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| SCSC_RS05380 (SCSC_1111) | - | 1086463..1086933 (-) | 471 | WP_006270651.1 | 8-oxo-dGTP diphosphatase | - |
| SCSC_RS05385 (SCSC_1112) | - | 1086934..1088031 (-) | 1098 | WP_006270698.1 | FAD-dependent oxidoreductase | - |
| SCSC_RS05390 (SCSC_1113) | - | 1088044..1088841 (-) | 798 | WP_006270711.1 | Nif3-like dinuclear metal center hexameric protein | - |
| SCSC_RS05395 (SCSC_1114) | - | 1088828..1089517 (-) | 690 | WP_006270709.1 | tRNA (adenine(22)-N(1))-methyltransferase TrmK | - |
| SCSC_RS05400 (SCSC_1115) | - | 1089860..1092325 (-) | 2466 | WP_006270674.1 | LTA synthase family protein | - |
| SCSC_RS05405 (SCSC_1116) | - | 1092325..1093992 (-) | 1668 | WP_006270682.1 | rhamnan synthesis F family protein | - |
| SCSC_RS05410 (SCSC_1117) | - | 1094007..1095209 (-) | 1203 | WP_006270670.1 | ABC transporter ATP-binding protein | - |
| SCSC_RS05415 (SCSC_1118) | - | 1095209..1096015 (-) | 807 | WP_006270692.1 | ABC transporter permease | - |
| SCSC_RS05420 (SCSC_1119) | - | 1096018..1096953 (-) | 936 | WP_006270702.1 | glycosyltransferase family 2 protein | - |
| SCSC_RS05425 (SCSC_1120) | - | 1096950..1098098 (-) | 1149 | WP_006270705.1 | glycosyltransferase family 1 protein | - |
| SCSC_RS05430 (SCSC_1121) | - | 1098287..1099531 (-) | 1245 | WP_006270680.1 | glycosyltransferase family 4 protein | - |
| SCSC_RS05435 (SCSC_1122) | - | 1099535..1100842 (-) | 1308 | WP_037566263.1 | DUF2142 domain-containing protein | - |
| SCSC_RS05440 (SCSC_1123) | - | 1100814..1103801 (-) | 2988 | WP_006270684.1 | rhamnan synthesis F family protein | - |
| SCSC_RS05445 (SCSC_1124) | - | 1103825..1104607 (-) | 783 | WP_006270716.1 | glycosyltransferase family 2 protein | - |
| SCSC_RS05450 (SCSC_1125) | - | 1104597..1104956 (-) | 360 | WP_006270722.1 | DUF2304 domain-containing protein | - |
| SCSC_RS05455 (SCSC_1126) | - | 1104956..1105672 (-) | 717 | WP_006270700.1 | glycosyltransferase family 2 protein | - |
| SCSC_RS05460 (SCSC_1127) | - | 1105669..1106640 (-) | 972 | WP_006270694.1 | glycosyltransferase | - |
| SCSC_RS05465 (SCSC_1128) | - | 1106667..1107614 (-) | 948 | WP_006270721.1 | glycosyltransferase family A protein | - |
| SCSC_RS05470 | - | 1107621..1108895 (-) | 1275 | WP_037566280.1 | lipopolysaccharide biosynthesis protein | - |
| SCSC_RS05475 (SCSC_1129) | rfbD | 1108967..1109821 (-) | 855 | WP_006270689.1 | dTDP-4-dehydrorhamnose reductase | - |
| SCSC_RS05480 (SCSC_1130) | - | 1109942..1111153 (-) | 1212 | WP_006270654.1 | hypothetical protein | - |
| SCSC_RS05485 (SCSC_1131) | - | 1111196..1112125 (-) | 930 | WP_037566268.1 | glycosyltransferase family 2 protein | - |
| SCSC_RS05490 (SCSC_1132) | - | 1112473..1112958 (-) | 486 | WP_003068625.1 | thioesterase family protein | - |
| SCSC_RS09425 (SCSC_1133) | - | 1113414..1113536 (-) | 123 | WP_006270720.1 | hypothetical protein | - |
| SCSC_RS05495 (SCSC_1134) | - | 1113926..1114846 (+) | 921 | WP_022524552.1 | IS30 family transposase | - |
| SCSC_RS05500 | - | 1114877..1115140 (+) | 264 | Protein_1068 | SinI family restriction endonuclease | - |
| SCSC_RS05505 (SCSC_1135) | - | 1115181..1116557 (-) | 1377 | WP_006270446.1 | DNA cytosine methyltransferase | - |
| SCSC_RS05510 (SCSC_1136) | - | 1116634..1117098 (-) | 465 | WP_006270426.1 | hypothetical protein | - |
| SCSC_RS05515 (SCSC_1137) | - | 1117300..1118982 (-) | 1683 | WP_006270433.1 | recombinase family protein | - |
| SCSC_RS05520 (SCSC_1138) | - | 1119066..1119233 (-) | 168 | WP_006270451.1 | hypothetical protein | - |
| SCSC_RS05525 (SCSC_1139) | - | 1119723..1120133 (-) | 411 | WP_006270427.1 | sigma-70 family RNA polymerase sigma factor | - |
| SCSC_RS05530 (SCSC_1140) | - | 1120366..1122114 (-) | 1749 | WP_006270455.1 | ABC transporter ATP-binding protein | - |
| SCSC_RS05535 (SCSC_1141) | - | 1122114..1123883 (-) | 1770 | WP_006270438.1 | ABC transporter ATP-binding protein | - |
| SCSC_RS05540 (SCSC_1142) | - | 1123980..1124936 (-) | 957 | WP_006270430.1 | AraC family transcriptional regulator | - |
| SCSC_RS05545 (SCSC_1143) | - | 1124939..1126411 (-) | 1473 | WP_006270441.1 | ABC transporter ATP-binding protein | - |
| SCSC_RS05550 (SCSC_1144) | - | 1126421..1127137 (-) | 717 | WP_006270439.1 | energy-coupling factor transporter transmembrane component T | - |
| SCSC_RS05555 (SCSC_1145) | - | 1127137..1127571 (-) | 435 | WP_198429516.1 | MptD family putative ECF transporter S component | - |
| SCSC_RS09470 (SCSC_1146) | - | 1127546..1127743 (-) | 198 | WP_306302101.1 | MptD family putative ECF transporter S component | - |
| SCSC_RS05560 (SCSC_1147) | mobC | 1128093..1128443 (+) | 351 | WP_006270454.1 | plasmid mobilization relaxosome protein MobC | - |
| SCSC_RS05565 (SCSC_1148) | - | 1128449..1129780 (+) | 1332 | WP_006270436.1 | relaxase/mobilization nuclease domain-containing protein | - |
| SCSC_RS05570 (SCSC_1149) | - | 1129805..1130542 (-) | 738 | WP_006270449.1 | TatD family hydrolase | - |
| SCSC_RS05575 (SCSC_1150) | qatC | 1130535..1131821 (-) | 1287 | WP_006270448.1 | Qat anti-phage system QueC-like protein QatC | - |
| SCSC_RS05580 (SCSC_1151) | - | 1131824..1132609 (-) | 786 | WP_006270445.1 | hypothetical protein | - |
| SCSC_RS05585 (SCSC_1152) | - | 1132620..1134440 (-) | 1821 | WP_006270453.1 | P-loop NTPase fold protein | - |
| SCSC_RS05590 (SCSC_1153) | - | 1134445..1134654 (-) | 210 | WP_006270432.1 | helix-turn-helix transcriptional regulator | - |
| SCSC_RS05595 (SCSC_1154) | - | 1134795..1135454 (-) | 660 | WP_006270421.1 | hypothetical protein | - |
| SCSC_RS05600 | - | 1135497..1144217 (-) | 8721 | WP_006270425.1 | helicase-related protein | - |
| SCSC_RS05605 (SCSC_1155) | - | 1144287..1145294 (-) | 1008 | WP_006270429.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| SCSC_RS05610 (SCSC_1156) | - | 1145287..1145892 (-) | 606 | WP_000612353.1 | DUF6088 family protein | - |
| SCSC_RS05615 (SCSC_1157) | - | 1145981..1147684 (-) | 1704 | WP_006270428.1 | DNA topoisomerase 3 | - |
| SCSC_RS05620 (SCSC_1158) | - | 1147772..1150774 (-) | 3003 | WP_232565286.1 | VaFE repeat-containing surface-anchored protein | - |
| SCSC_RS05625 (SCSC_1159) | - | 1150925..1152454 (-) | 1530 | WP_006270456.1 | DUF4366 domain-containing protein | - |
| SCSC_RS05630 (SCSC_1160) | - | 1152429..1152668 (-) | 240 | WP_006270422.1 | hypothetical protein | - |
| SCSC_RS05635 (SCSC_1161) | - | 1152681..1154813 (-) | 2133 | WP_006270452.1 | CHAP domain-containing protein | - |
| SCSC_RS05640 (SCSC_1162) | - | 1154817..1157246 (-) | 2430 | WP_006270443.1 | ATP-binding protein | - |
| SCSC_RS05645 | - | 1157158..1157547 (-) | 390 | WP_022524555.1 | PrgI family protein | - |
| SCSC_RS05650 (SCSC_1163) | - | 1157551..1157814 (-) | 264 | WP_006270447.1 | hypothetical protein | - |
| SCSC_RS05655 (SCSC_1164) | - | 1157832..1158695 (-) | 864 | WP_000466908.1 | CD0415/CD1112 family protein | - |
| SCSC_RS05660 (SCSC_1165) | - | 1158715..1158930 (-) | 216 | WP_000863833.1 | Maff2 family protein | - |
| SCSC_RS05665 (SCSC_1166) | - | 1158934..1159245 (-) | 312 | WP_006270424.1 | hypothetical protein | - |
| SCSC_RS05670 (SCSC_1167) | - | 1159409..1161193 (-) | 1785 | WP_006270444.1 | type IV secretory system conjugative DNA transfer family protein | - |
| SCSC_RS05675 (SCSC_1168) | - | 1161190..1161675 (-) | 486 | WP_006270437.1 | PcfB family protein | - |
| SCSC_RS05680 (SCSC_1169) | - | 1161672..1162523 (-) | 852 | WP_006270434.1 | ATP-binding protein | - |
| SCSC_RS05685 | - | 1162520..1163277 (-) | 758 | Protein_1106 | replication initiator protein A | - |
| SCSC_RS05690 | - | 1163364..1163645 (-) | 282 | WP_115342918.1 | CD1845 family protein | - |
| SCSC_RS05695 (SCSC_1172) | - | 1164051..1165133 (-) | 1083 | WP_115342919.1 | acyltransferase family protein | - |
| SCSC_RS05700 (SCSC_1173) | - | 1165147..1167090 (-) | 1944 | WP_006270015.1 | alkyl sulfatase dimerization domain-containing protein | - |
Sequence
Protein
Download Length: 334 a.a. Molecular weight: 37114.26 Da Isoelectric Point: 5.8327
>NTDB_id=66570 SCSC_RS05345 WP_006270669.1 1079008..1080012(-) (ccpA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVERLTKNNKKIAFVSGPLVDDINGKIRLIGYKEALKKAKLSYSEGLVFESKYSYEDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKDVNIPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERRSTRK
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVERLTKNNKKIAFVSGPLVDDINGKIRLIGYKEALKKAKLSYSEGLVFESKYSYEDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKDVNIPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERRSTRK
Nucleotide
Download Length: 1005 bp
>NTDB_id=66570 SCSC_RS05345 WP_006270669.1 1079008..1080012(-) (ccpA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGAACACAGACGATACTGTAACGATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTAGT
AAACGGCAATAAAAATGTAAAGGAAAATACAAGAAAAAAAGTCTTGGAAGTCATTGATCGCCTTGACTATCGACCAAATG
CAGTTGCTCGTGGACTTGCCAGTAAGAAAACGACAACAGTAGGAGTTGTCATTCCAAACATTACAAGCAGTTATTTTGCA
ACGCTTGCGAAAGGAATTGATGACATCGCAGAGATGTATAAGTATAATATTGTTTTGGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCTGTTGTCAATACCTTGTTCTCAAAACAAGTGGACGGCATTATCTTTATGGGATATCATCTAACAGAAA
AGATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCGGTTGTACTTGCAGGAACGGTTGACGTGGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCAGTAGAGCGCCTCACTAAAAACAATAAAAAAATTGCTTTTGTGAG
TGGACCTTTGGTAGATGATATAAATGGTAAGATTCGTTTGATTGGTTACAAAGAAGCGTTGAAAAAAGCAAAACTTTCTT
ATAGTGAAGGGCTTGTCTTTGAGTCTAAATACAGCTATGAGGATGGCTATCAATTGGCAGAGCGTGTCATTGCTTCTAAA
GCGACAGCGGCCTTTGTGACTGGCGATGAACTGGCAGCTGGATTGTTAAATGGCTTATCAGACAAAGATGTAAATATACC
AGAAGATTTTGAAATCATTACTAGTGATGATTCGCAGGTAGCACGTTTTACTCGTCCGAATTTGACGACAATTGGACAAC
CTTTGTACGATCTTGGTGCGATTAGTATGCGCATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTG
GTGTTAGCTCATGGTCTTATTGAGCGCCGTTCAACAAGGAAGTAA
ATGAACACAGACGATACTGTAACGATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTAGT
AAACGGCAATAAAAATGTAAAGGAAAATACAAGAAAAAAAGTCTTGGAAGTCATTGATCGCCTTGACTATCGACCAAATG
CAGTTGCTCGTGGACTTGCCAGTAAGAAAACGACAACAGTAGGAGTTGTCATTCCAAACATTACAAGCAGTTATTTTGCA
ACGCTTGCGAAAGGAATTGATGACATCGCAGAGATGTATAAGTATAATATTGTTTTGGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCTGTTGTCAATACCTTGTTCTCAAAACAAGTGGACGGCATTATCTTTATGGGATATCATCTAACAGAAA
AGATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCGGTTGTACTTGCAGGAACGGTTGACGTGGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCAGTAGAGCGCCTCACTAAAAACAATAAAAAAATTGCTTTTGTGAG
TGGACCTTTGGTAGATGATATAAATGGTAAGATTCGTTTGATTGGTTACAAAGAAGCGTTGAAAAAAGCAAAACTTTCTT
ATAGTGAAGGGCTTGTCTTTGAGTCTAAATACAGCTATGAGGATGGCTATCAATTGGCAGAGCGTGTCATTGCTTCTAAA
GCGACAGCGGCCTTTGTGACTGGCGATGAACTGGCAGCTGGATTGTTAAATGGCTTATCAGACAAAGATGTAAATATACC
AGAAGATTTTGAAATCATTACTAGTGATGATTCGCAGGTAGCACGTTTTACTCGTCCGAATTTGACGACAATTGGACAAC
CTTTGTACGATCTTGGTGCGATTAGTATGCGCATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTG
GTGTTAGCTCATGGTCTTATTGAGCGCCGTTCAACAAGGAAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccpA | Streptococcus gordonii str. Challis substr. CH1 |
90.419 |
100 |
0.904 |
| ccpA | Streptococcus pneumoniae D39 |
87.425 |
100 |
0.874 |
| ccpA | Lactococcus lactis subsp. lactis strain DGCC12653 |
58.006 |
99.102 |
0.575 |