Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SCSC_RS02165 Genome accession   NZ_AP014647
Coordinates   427081..428382 (+) Length   433 a.a.
NCBI ID   WP_037565799.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 422081..433382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS02140 (SCSC_0440) cas1c 422188..423228 (+) 1041 WP_006269871.1 type I-C CRISPR-associated endonuclease Cas1c -
  SCSC_RS02145 (SCSC_0441) cas2 423239..423532 (+) 294 WP_006269853.1 CRISPR-associated endonuclease Cas2 -
  SCSC_RS02150 (SCSC_0442) - 424987..425154 (+) 168 Protein_398 cell filamentation protein Fic -
  SCSC_RS02155 (SCSC_0443) cysK 425360..426289 (-) 930 WP_006269877.1 cysteine synthase A -
  SCSC_RS02160 (SCSC_0444) - 426389..427024 (-) 636 WP_006269864.1 YigZ family protein -
  SCSC_RS02165 (SCSC_0445) comFA/cflA 427081..428382 (+) 1302 WP_037565799.1 DEAD/DEAH box helicase Machinery gene
  SCSC_RS02170 (SCSC_0446) - 428379..429044 (+) 666 WP_003043136.1 ComF family protein -
  SCSC_RS02175 (SCSC_0447) raiA 429123..429665 (+) 543 WP_003032381.1 ribosome-associated translation inhibitor RaiA -
  SCSC_RS02180 (SCSC_0448) rsmD 429863..430402 (+) 540 WP_037565796.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SCSC_RS02185 (SCSC_0449) coaD 430392..430889 (+) 498 WP_003070176.1 pantetheine-phosphate adenylyltransferase -
  SCSC_RS02190 (SCSC_0450) sepM 430870..431925 (+) 1056 WP_003070174.1 SepM family pheromone-processing serine protease Regulator
  SCSC_RS02195 (SCSC_0451) - 432212..432769 (+) 558 WP_003070172.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49315.23 Da        Isoelectric Point: 8.1172

>NTDB_id=66549 SCSC_RS02165 WP_037565799.1 427081..428382(+) (comFA/cflA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MIELQDCLGRMFTKAQLPAELQLYAQTLPAMKEEKGKLCCNRCGQAVDKERHQLPIGAYYCRSCLILGRVRSDEELYYFP
QEEFPKADVLKWQGTLTEFQAKVSQRLVEAVAKRKDSLVHAVTGAGKTEMIYQVVAQVIDQGGAVCLASPRIDVCLELYR
RLKIDFACDISLLHGESEAYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKEQGTKIFLTATS
TDELDKRVSKGELSRLSLPRRFHGNPLIVPQKVWLENFQKYLNQKKLVPKLEQFVKKQRKTGFPLLIFASEIKRGQEFAE
VLQNNFPNEKVGFVASTTENRLDIVEKFRQKDITILVTTTILERGVTFPCVDVFVVEANHCLFSRSALVQIAGRVGRSME
RPTGELIFFHDGTTMAIEKAIKEIREMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=66549 SCSC_RS02165 WP_037565799.1 427081..428382(+) (comFA/cflA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGATAGAATTACAAGATTGCTTAGGTCGTATGTTTACAAAAGCACAACTACCAGCAGAATTGCAATTATATGCGCAAAC
TTTACCAGCAATGAAAGAAGAAAAAGGGAAATTATGTTGCAATCGCTGTGGGCAAGCAGTTGATAAAGAAAGACACCAAC
TGCCAATAGGTGCTTACTACTGTAGATCCTGCTTGATCTTAGGAAGGGTCAGAAGTGATGAAGAACTCTATTATTTTCCA
CAGGAAGAGTTTCCTAAAGCGGATGTCTTAAAATGGCAAGGAACGTTAACAGAATTTCAAGCCAAGGTTTCTCAAAGACT
TGTGGAGGCAGTTGCCAAGCGAAAAGATAGCTTGGTCCATGCAGTCACGGGAGCTGGAAAAACAGAAATGATCTATCAGG
TGGTAGCACAAGTTATTGATCAAGGCGGGGCCGTCTGCTTGGCTAGCCCACGAATTGATGTCTGTTTAGAACTTTATCGT
AGACTGAAAATAGATTTTGCTTGTGATATTTCACTCCTGCATGGCGAATCAGAAGCGTATTTTCGCAGTCCTCTCGTAAT
TGCCACAACGCATCAGCTTCTCAAATTTTACCGAGCATTTGATCTGCTCATCGTTGACGAAGTGGATGCCTTTCCTTATG
TAGACAATCCAATGCTTTATCATGCGGTTCATCAAGCAGTCAAAGAACAAGGCACGAAAATTTTCTTGACAGCAACCTCC
ACAGATGAGCTGGACAAAAGAGTTAGCAAGGGAGAGTTGAGCCGCTTAAGTCTCCCTAGACGTTTTCATGGTAACCCTTT
AATTGTTCCTCAAAAAGTTTGGTTGGAAAATTTTCAAAAATACTTGAATCAAAAAAAGCTAGTTCCTAAGTTGGAACAAT
TTGTTAAAAAGCAAAGAAAAACAGGTTTTCCTCTTCTCATTTTTGCTTCTGAGATTAAAAGAGGACAAGAATTTGCAGAG
GTTCTCCAAAACAATTTCCCTAATGAAAAAGTTGGCTTTGTTGCTTCGACGACTGAAAATCGACTAGATATTGTAGAGAA
ATTTCGTCAAAAGGATATCACAATTTTAGTAACAACGACGATTCTAGAACGTGGTGTAACTTTTCCTTGTGTAGATGTTT
TTGTGGTGGAGGCTAACCATTGTCTGTTTAGTCGCAGTGCTTTGGTACAAATTGCTGGTCGTGTTGGTCGTAGTATGGAG
CGACCAACAGGCGAGTTAATCTTTTTTCATGATGGTACAACTATGGCGATAGAAAAAGCTATTAAAGAAATTCGGGAGAT
GAATCAGGAGGCTGGTTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-397)

DEAD/DEAH box helicase (DEAD)

(101-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

70.423

98.383

0.693
  comFA/cflA Streptococcus pneumoniae D39

69.86

98.845

0.691
  comFA/cflA Streptococcus pneumoniae R6

69.86

98.845

0.691
  comFA/cflA Streptococcus pneumoniae Rx1

69.86

98.845

0.691
  comFA/cflA Streptococcus mitis SK321

69.953

98.383

0.688
  comFA/cflA Streptococcus pneumoniae TIGR4

69.626

98.845

0.688
  comFA Lactococcus lactis subsp. cremoris KW2

55.528

91.917

0.51
  comFA Latilactobacillus sakei subsp. sakei 23K

41.109

100

0.411
  comFA Bacillus subtilis subsp. subtilis str. 168

40.25

92.379

0.372

Multiple sequence alignment