Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MNU43_RS04365 Genome accession   NZ_CP093205
Coordinates   950728..951444 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain TSM-36     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 945728..956444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNU43_RS04350 (MNU43_04345) - 947009..947962 (+) 954 WP_002457062.1 LacI family DNA-binding transcriptional regulator -
  MNU43_RS04355 (MNU43_04350) - 948222..949694 (+) 1473 WP_001830011.1 sucrose-6-phosphate hydrolase -
  MNU43_RS04360 (MNU43_04355) - 949701..950660 (+) 960 WP_002457063.1 carbohydrate kinase -
  MNU43_RS04365 (MNU43_04360) agrA 950728..951444 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  MNU43_RS04370 (MNU43_04365) agrC 951461..952750 (-) 1290 WP_002457064.1 quorum-sensing sensor histidine kinase AgrC -
  MNU43_RS04375 (MNU43_04370) agrD 952775..952915 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  MNU43_RS04380 (MNU43_04375) - 952921..953484 (-) 564 WP_002457915.1 accessory gene regulator AgrB -
  MNU43_RS04385 (MNU43_04380) hld 953801..953878 (+) 78 WP_002494082.1 delta-hemolysin -
  MNU43_RS04390 (MNU43_04385) - 954259..955044 (-) 786 WP_002469371.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=662457 MNU43_RS04365 WP_001829999.1 950728..951444(-) (agrA) [Staphylococcus epidermidis strain TSM-36]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=662457 MNU43_RS04365 WP_001829999.1 950728..951444(-) (agrA) [Staphylococcus epidermidis strain TSM-36]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTCGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGGCTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374