Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MNU35_RS04340 Genome accession   NZ_CP093170
Coordinates   928541..929257 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain TMDU-128     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 923541..934257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNU35_RS04325 (MNU35_04330) - 924822..925775 (+) 954 WP_254106327.1 LacI family DNA-binding transcriptional regulator -
  MNU35_RS04330 (MNU35_04335) - 926035..927507 (+) 1473 WP_119557524.1 sucrose-6-phosphate hydrolase -
  MNU35_RS04335 (MNU35_04340) - 927514..928473 (+) 960 WP_002447516.1 carbohydrate kinase -
  MNU35_RS04340 (MNU35_04345) agrA 928541..929257 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  MNU35_RS04345 (MNU35_04350) agrC 929274..930563 (-) 1290 WP_254106329.1 quorum-sensing sensor histidine kinase AgrC -
  MNU35_RS04350 (MNU35_04355) agrD 930589..930729 (-) 141 WP_002468352.1 cyclic lactone autoinducer peptide AgrD -
  MNU35_RS04355 (MNU35_04360) - 930735..931298 (-) 564 WP_119557520.1 accessory gene regulator AgrB -
  MNU35_RS04360 (MNU35_04365) hld 931615..931692 (+) 78 WP_002494082.1 delta-hemolysin -
  MNU35_RS04365 (MNU35_04370) - 932073..932858 (-) 786 WP_182579233.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=662100 MNU35_RS04340 WP_001829999.1 928541..929257(-) (agrA) [Staphylococcus epidermidis strain TMDU-128]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=662100 MNU35_RS04340 WP_001829999.1 928541..929257(-) (agrA) [Staphylococcus epidermidis strain TMDU-128]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAACGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACGAGTCACAGTGAACTCACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
AGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374