Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   MKD48_RS06335 Genome accession   NZ_CP092475
Coordinates   1212243..1213313 (+) Length   356 a.a.
NCBI ID   WP_000776403.1    Uniprot ID   -
Organism   Staphylococcus aureus strain P5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1207243..1218313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKD48_RS06305 - 1207666..1209129 (+) 1464 WP_001017872.1 rhomboid family intramembrane serine protease -
  MKD48_RS06310 - 1209110..1209313 (+) 204 WP_000087561.1 YqgQ family protein -
  MKD48_RS06315 - 1209310..1210296 (+) 987 WP_000161315.1 ROK family glucokinase -
  MKD48_RS06320 - 1210296..1210625 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  MKD48_RS06325 - 1210622..1211245 (+) 624 WP_001223006.1 MBL fold metallo-hydrolase -
  MKD48_RS06330 comGA 1211297..1212271 (+) 975 WP_000697215.1 competence type IV pilus ATPase ComGA Machinery gene
  MKD48_RS06335 comGB 1212243..1213313 (+) 1071 WP_000776403.1 competence type IV pilus assembly protein ComGB Machinery gene
  MKD48_RS06340 comGC 1213327..1213638 (+) 312 WP_248313621.1 competence type IV pilus major pilin ComGC Machinery gene
  MKD48_RS06345 comGD 1213616..1214062 (+) 447 WP_075583651.1 competence type IV pilus minor pilin ComGD Machinery gene
  MKD48_RS06350 comGE 1214049..1214348 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  MKD48_RS06355 comGF 1214266..1214763 (+) 498 WP_029697681.1 competence type IV pilus minor pilin ComGF Machinery gene
  MKD48_RS06360 - 1214860..1215006 (+) 147 WP_001789879.1 hypothetical protein -
  MKD48_RS06365 - 1214996..1215520 (+) 525 WP_001015122.1 shikimate kinase -
  MKD48_RS06370 gcvT 1215679..1216770 (+) 1092 WP_000093355.1 glycine cleavage system aminomethyltransferase GcvT -
  MKD48_RS06375 gcvPA 1216790..1218136 (+) 1347 WP_000019688.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41487.99 Da        Isoelectric Point: 10.1030

>NTDB_id=657899 MKD48_RS06335 WP_000776403.1 1212243..1213313(+) (comGB) [Staphylococcus aureus strain P5]
MKLQWINTFKLHSKKRQLSKAQQIDLLLNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=657899 MKD48_RS06335 WP_000776403.1 1212243..1213313(+) (comGB) [Staphylococcus aureus strain P5]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTTAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGCACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAACCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATCATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCGATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAAATTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CGGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTATTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTACCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGAAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTGGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.438

100

0.994
  comGB Staphylococcus aureus N315

99.438

100

0.994