Detailed information NTG0656227

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MF598_RS02605
• Genome accession: NZ_CP092185
• Coordinates: 513029..514192 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain K203
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 508029..519192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MF598_RS02585 (MF598_02585)	-	508430..509626 (+)	1197	WP_224223857.1	glycosyltransferase	-
MF598_RS02590 (MF598_02590)	-	509759..510835 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
MF598_RS02595 (MF598_02595)	-	510934..512154 (-)	1221	WP_105937243.1	LCP family protein	-
MF598_RS02600 (MF598_02600)	-	512159..512806 (-)	648	WP_007614107.1	YigZ family protein	-
MF598_RS02605 (MF598_02605)	degS	513029..514192 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MF598_RS02610 (MF598_02610)	degU	514269..514958 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MF598_RS02615 (MF598_02615)	-	515056..515904 (+)	849	WP_045209019.1	DegV family protein	-
MF598_RS02620 (MF598_02620)	comFA	516013..517398 (+)	1386	WP_224223856.1	DEAD/DEAH box helicase	Machinery gene
MF598_RS02625 (MF598_02625)	-	517456..517740 (+)	285	WP_003151389.1	competence protein ComFB	-
MF598_RS02630 (MF598_02630)	comFC	517746..518435 (+)	690	WP_198161198.1	phosphoribosyltransferase family protein	Machinery gene
MF598_RS02635 (MF598_02635)	-	518509..518928 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=656227 MF598_RS02605 WP_007407484.1 513029..514192(+) (degS) [Bacillus velezensis strain K203]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=656227 MF598_RS02605 WP_007407484.1 513029..514192(+) (degS) [Bacillus velezensis strain K203]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCATGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGCGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTAGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951