Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   MCF40_RS07225 Genome accession   NZ_CP092072
Coordinates   1568900..1569211 (-) Length   103 a.a.
NCBI ID   WP_000921699.1    Uniprot ID   A0A7U7JUV8
Organism   Staphylococcus argenteus strain 1710042798     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1563900..1574211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MCF40_RS07190 (MCF40_07190) gcvPA 1564403..1565749 (-) 1347 WP_031787255.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  MCF40_RS07195 (MCF40_07195) gcvT 1565768..1566859 (-) 1092 WP_000093342.1 glycine cleavage system aminomethyltransferase GcvT -
  MCF40_RS07200 (MCF40_07200) - 1567016..1567540 (-) 525 WP_031787256.1 shikimate kinase -
  MCF40_RS07205 (MCF40_07205) - 1567527..1567676 (-) 150 WP_072324192.1 hypothetical protein -
  MCF40_RS07210 (MCF40_07210) comGF 1567775..1568230 (-) 456 WP_078097699.1 competence type IV pilus minor pilin ComGF Machinery gene
  MCF40_RS07215 (MCF40_07215) comGE 1568190..1568489 (-) 300 WP_031787259.1 hypothetical protein Machinery gene
  MCF40_RS07220 (MCF40_07220) comGD 1568476..1568922 (-) 447 WP_072324131.1 competence type IV pilus minor pilin ComGD Machinery gene
  MCF40_RS07225 (MCF40_07225) comGC 1568900..1569211 (-) 312 WP_000921699.1 competence type IV pilus major pilin ComGC Machinery gene
  MCF40_RS07230 (MCF40_07230) comGB 1569226..1570296 (-) 1071 WP_031787261.1 competence type IV pilus assembly protein ComGB Machinery gene
  MCF40_RS07235 (MCF40_07235) comGA 1570268..1571242 (-) 975 WP_031787262.1 competence type IV pilus ATPase ComGA Machinery gene
  MCF40_RS07240 (MCF40_07240) - 1571294..1571917 (-) 624 WP_031787263.1 MBL fold metallo-hydrolase -
  MCF40_RS07245 (MCF40_07245) - 1571914..1572243 (-) 330 WP_001018874.1 MTH1187 family thiamine-binding protein -
  MCF40_RS07250 (MCF40_07250) - 1572243..1573229 (-) 987 WP_000161316.1 ROK family glucokinase -
  MCF40_RS07255 (MCF40_07255) - 1573229..1573429 (-) 201 WP_000087563.1 YqgQ family protein -

Sequence

Protein


Download         Length: 103 a.a.        Molecular weight: 11189.29 Da        Isoelectric Point: 9.1992

>NTDB_id=655775 MCF40_RS07225 WP_000921699.1 1568900..1569211(-) (comGC) [Staphylococcus argenteus strain 1710042798]
MLKVIKKAKAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIDELVADGFI
KEAQKTCKSGETISISNGEAIAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=655775 MCF40_RS07225 WP_000921699.1 1568900..1569211(-) (comGC) [Staphylococcus argenteus strain 1710042798]
ATGTTGAAAGTTATTAAAAAAGCTAAAGCATTTACTTTAATAGAAATGCTATTAGTTCTATTAATTATAAGCTTATTATT
AATTTTAATTATTCCAAATATCGCGAAACAAACAGCGCATATCCAATCTACTGGATGTAATGCACAAGTTAAAATGGTTA
ATAGTCAAATTGAAGCTTATGCATTGAAACACAATAGAAATCCTTCTTCAATTGATGAACTAGTAGCTGATGGCTTTATT
AAAGAGGCACAAAAAACATGTAAATCTGGTGAAACAATATCGATTAGTAATGGAGAAGCTATTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7JUV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

90.291

100

0.903
  comGC Staphylococcus aureus N315

90.291

100

0.903
  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456
  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427
  comGC/cglC Streptococcus mitis SK321

51.163

83.495

0.427
  comYC Streptococcus gordonii str. Challis substr. CH1

43.878

95.146

0.417
  comYC Streptococcus mutans UA159

48.235

82.524

0.398
  comYC Streptococcus mutans UA140

48.235

82.524

0.398
  comYC Streptococcus suis isolate S10

51.282

75.728

0.388
  comGC Lactococcus lactis subsp. cremoris KW2

48.78

79.612

0.388
  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369