Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU08_RS37040 Genome accession   NZ_CP108128
Coordinates   8461407..8462069 (+) Length   220 a.a.
NCBI ID   WP_266850320.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00197     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8456407..8467069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU08_RS37020 (OHU08_36980) - 8457415..8458302 (+) 888 WP_406379986.1 GntR family transcriptional regulator -
  OHU08_RS37025 (OHU08_36985) - 8458425..8459033 (-) 609 WP_385390889.1 ankyrin repeat domain-containing protein -
  OHU08_RS37030 (OHU08_36990) - 8459296..8459850 (-) 555 WP_164375359.1 heme-binding protein -
  OHU08_RS37035 (OHU08_36995) - 8460214..8461410 (+) 1197 WP_406380681.1 sensor histidine kinase -
  OHU08_RS37040 (OHU08_37000) vraR 8461407..8462069 (+) 663 WP_266850320.1 response regulator transcription factor Regulator
  OHU08_RS37045 (OHU08_37005) - 8462123..8462539 (-) 417 WP_366269588.1 carboxymuconolactone decarboxylase family protein -
  OHU08_RS37050 (OHU08_37010) - 8462568..8463035 (-) 468 WP_356069145.1 nuclear transport factor 2 family protein -
  OHU08_RS37055 (OHU08_37015) - 8463161..8463994 (+) 834 WP_406379989.1 alpha/beta fold hydrolase -
  OHU08_RS37060 (OHU08_37020) - 8464022..8464504 (+) 483 WP_406379991.1 hypothetical protein -
  OHU08_RS37065 (OHU08_37025) - 8464853..8465680 (+) 828 WP_351487630.1 alpha/beta hydrolase -
  OHU08_RS37070 (OHU08_37030) - 8465783..8466039 (+) 257 Protein_7312 hypothetical protein -
  OHU08_RS37075 (OHU08_37035) - 8466068..8466415 (+) 348 WP_406379993.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23029.35 Da        Isoelectric Point: 4.9306

>NTDB_id=654547 OHU08_RS37040 WP_266850320.1 8461407..8462069(+) (vraR) [Streptomyces sp. NBC_00197]
MTAAPGAPDASRPPVRILLCDDHAVVRAGLLALLDSAPDIEVVGEAGTGEEALALSAKLAPDVVLMDLQLGDGIDGVETT
RRLTAAPGATPHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIQAAAQGRTALSAPVASRVMANLRSPRPTLT
DRERDILTQLAQGLGNREIAKALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 663 bp        

>NTDB_id=654547 OHU08_RS37040 WP_266850320.1 8461407..8462069(+) (vraR) [Streptomyces sp. NBC_00197]
ATGACAGCCGCCCCCGGTGCGCCCGACGCCTCCCGGCCCCCCGTCCGCATCCTGCTGTGCGACGACCACGCCGTCGTCCG
CGCCGGACTGCTCGCCCTGCTCGACAGCGCGCCGGACATCGAGGTCGTCGGCGAGGCGGGCACGGGCGAGGAGGCGCTCG
CCCTCAGCGCCAAGCTCGCCCCCGACGTGGTCCTCATGGACCTCCAGCTCGGCGACGGCATCGACGGCGTGGAGACCACC
CGCCGGCTCACCGCGGCTCCCGGCGCCACGCCGCACGTCCTGGTGCTCACGACGTACGACACCGACGCCGACATCACGCG
GGCCATCGAGGCCGGGGCGACCGGCTACCTGCTGAAGGCCGAGCGCCCGGAGGAACTGTTCGCCGCGATCCAGGCCGCCG
CCCAGGGGCGCACGGCCCTGTCGGCCCCGGTCGCGAGCCGGGTGATGGCCAACCTGCGCAGCCCGCGGCCCACGCTGACC
GACCGCGAACGGGACATCCTGACCCAGCTCGCCCAGGGCCTCGGCAACCGCGAGATCGCGAAGGCCCTGTTCATCAGCGA
GGCGACGGTCAAGACCCACCTCGGCCGCATCTACGACAAGCTCGGCGTCGACACCCGGGCGGGCGCGGTGTCGGTCGCGA
AGGAACAGCGTCTGCTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-131)

Bacterial regulatory proteins, luxR family (GerE)

(158-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.736

96.364

0.364