Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS17135 Genome accession   NZ_CP108081
Coordinates   3854207..3854893 (-) Length   228 a.a.
NCBI ID   WP_328844538.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3849207..3859893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS17110 (OG718_17095) - 3849312..3850364 (-) 1053 WP_328844537.1 ABC transporter substrate-binding protein -
  OG718_RS17115 (OG718_17100) - 3850855..3851085 (-) 231 Protein_3418 ABC transporter ATP-binding protein -
  OG718_RS17120 (OG718_17105) - 3851246..3851938 (+) 693 WP_143638141.1 response regulator -
  OG718_RS17125 (OG718_17110) - 3852025..3853617 (-) 1593 WP_143638139.1 cation acetate symporter -
  OG718_RS17130 (OG718_17115) - 3853614..3854102 (-) 489 WP_143638137.1 DUF485 domain-containing protein -
  OG718_RS17135 (OG718_17120) vraR 3854207..3854893 (-) 687 WP_328844538.1 response regulator transcription factor Regulator
  OG718_RS17140 (OG718_17125) - 3854890..3856041 (-) 1152 WP_143638134.1 histidine kinase -
  OG718_RS17145 (OG718_17130) - 3856038..3856562 (-) 525 WP_328844539.1 DUF1453 domain-containing protein -
  OG718_RS17150 (OG718_17135) - 3856826..3858949 (-) 2124 WP_143638131.1 DNA topoisomerase IV subunit B -
  OG718_RS17155 (OG718_17140) - 3859390..3859620 (+) 231 WP_055513118.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24211.64 Da        Isoelectric Point: 5.3953

>NTDB_id=652979 OG718_RS17135 WP_328844538.1 3854207..3854893(-) (vraR) [Streptomyces sp. NBC_00258]
MTEEEGGAPARVVVADDQTVVREGIVMLLGLLSGIEVVGAAADGHEAVRLVAELDPDVVLMDLRMPRCDGVEATRRIRAE
HPRTQVVVLTTYADDASLFPALRAGARGYLTKDAGGDEIVRAVRSVLSGDAGLSPGIQRRLLERLSEPEPAVPAQGTEAP
DGLTARETEVLVLIADGLTNQEIARRLHVSTATVKTHINNLFAKTGLKDRAQAVRYAFGKGLVRPPGG

Nucleotide


Download         Length: 687 bp        

>NTDB_id=652979 OG718_RS17135 WP_328844538.1 3854207..3854893(-) (vraR) [Streptomyces sp. NBC_00258]
ATGACGGAGGAGGAGGGCGGAGCACCGGCCCGTGTCGTCGTGGCGGACGATCAGACCGTGGTGCGCGAGGGCATCGTGAT
GCTGCTCGGGCTGCTGTCGGGGATCGAGGTCGTCGGGGCGGCCGCCGACGGGCACGAGGCCGTGCGGCTGGTGGCCGAAC
TCGACCCGGACGTCGTGCTGATGGACCTGCGCATGCCTCGCTGCGACGGGGTGGAGGCGACCAGACGAATCCGGGCCGAA
CACCCCAGGACGCAGGTTGTCGTGCTCACCACGTACGCGGACGACGCCTCGCTGTTCCCCGCGCTCAGGGCCGGGGCCCG
TGGCTATCTCACCAAGGACGCGGGCGGCGACGAGATCGTACGGGCCGTGCGGAGCGTGCTGTCCGGGGACGCAGGGCTCT
CCCCGGGCATTCAACGGCGCTTGCTGGAGCGGCTGTCCGAGCCGGAGCCGGCCGTTCCCGCGCAGGGCACCGAGGCGCCG
GACGGGCTCACCGCGCGGGAGACGGAGGTGCTCGTGCTGATCGCCGACGGTCTGACCAACCAGGAGATCGCCCGCAGGCT
CCATGTCTCGACGGCCACCGTGAAGACCCACATCAACAACCTGTTCGCCAAGACGGGGCTCAAGGATCGTGCGCAGGCGG
TCCGTTACGCCTTCGGGAAGGGACTTGTGCGGCCACCAGGGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(162-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

93.86

0.373