Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS26550 Genome accession   NZ_CP108055
Coordinates   5777632..5778297 (+) Length   221 a.a.
NCBI ID   WP_328749013.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5772632..5783297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS26530 (OHT57_26555) - 5772890..5774110 (+) 1221 WP_328753334.1 acyltransferase -
  OHT57_RS26535 (OHT57_26560) - 5774103..5775473 (+) 1371 WP_328749011.1 sensor histidine kinase -
  OHT57_RS26540 (OHT57_26565) vraR 5775470..5776144 (+) 675 WP_328749012.1 response regulator transcription factor Regulator
  OHT57_RS26545 (OHT57_26570) - 5776271..5777635 (+) 1365 WP_328753335.1 histidine kinase -
  OHT57_RS26550 (OHT57_26575) vraR 5777632..5778297 (+) 666 WP_328749013.1 response regulator transcription factor Regulator
  OHT57_RS26555 (OHT57_26580) - 5778321..5778635 (-) 315 WP_328749014.1 hypothetical protein -
  OHT57_RS26560 (OHT57_26585) - 5778632..5778877 (-) 246 WP_328749015.1 hypothetical protein -
  OHT57_RS26565 (OHT57_26590) - 5779015..5779419 (-) 405 WP_328749016.1 ATP-binding protein -
  OHT57_RS26570 (OHT57_26595) - 5779638..5780492 (+) 855 WP_328749017.1 helix-turn-helix transcriptional regulator -
  OHT57_RS26575 (OHT57_26600) - 5780489..5780689 (+) 201 WP_328749018.1 DUF397 domain-containing protein -
  OHT57_RS26580 (OHT57_26605) - 5780699..5781904 (+) 1206 WP_328749019.1 cytochrome P450 -
  OHT57_RS26585 (OHT57_26610) - 5781992..5782596 (+) 605 Protein_5250 Uma2 family endonuclease -
  OHT57_RS26590 (OHT57_26615) - 5782625..5782888 (-) 264 WP_328749020.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24034.77 Da        Isoelectric Point: 4.9706

>NTDB_id=652293 OHT57_RS26550 WP_328749013.1 5777632..5778297(+) (vraR) [Streptomyces sp. NBC_00285]
MTIRVLVADDQMMVREGFSVLLNAMPGIEVVGEAVNGREAVDRVRELAPDVVLMDIRMPELNGIEATREIVAADGTAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASAHQLADGVKVVASGEALLAPSVTRRLITEFAKLSESPRLIPSAHTAYGDLTY
RETEVLIHIAQGLSNFEMAERLMVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652293 OHT57_RS26550 WP_328749013.1 5777632..5778297(+) (vraR) [Streptomyces sp. NBC_00285]
ATGACCATCCGGGTCCTGGTCGCGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTGCTGCTGAACGCGATGCCGGG
CATCGAGGTGGTCGGTGAGGCCGTCAACGGCCGGGAGGCGGTCGACCGGGTCCGTGAACTCGCCCCGGACGTGGTCCTGA
TGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACGAGGGAGATCGTCGCGGCGGACGGCACGGCGAAGGTCCTG
GTCCTGACGACCTTCGACCTCGACGAGTACGTCTACCAGGCACTGCGCGCGGGAGCCTCGGGCTTCCTCCTCAAAGATGC
CTCGGCCCACCAACTCGCTGACGGAGTAAAGGTGGTGGCCTCCGGCGAGGCGCTCCTCGCGCCCTCCGTCACCCGGCGCC
TGATCACGGAGTTCGCCAAGCTCTCCGAGTCCCCCCGCCTCATACCCTCGGCGCACACGGCCTACGGCGACCTGACCTAC
CGCGAGACGGAAGTACTGATCCACATCGCCCAGGGCCTGTCGAACTTCGAGATGGCCGAGCGCCTGATGGTCGCGGAGTC
GACGATCAAGACCCACGTCAGCCGGGTCCTGGTGAAACTGGGCCTCAGGGACCGGACCCAGGCGGCGGTGTTCGCGTACG
AGGCGCGGTTGGTGACGCCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.743

98.643

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

41.935

98.19

0.412