Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS26540 Genome accession   NZ_CP108055
Coordinates   5775470..5776144 (+) Length   224 a.a.
NCBI ID   WP_328749012.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5770470..5781144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS26520 (OHT57_26545) - 5770488..5771450 (+) 963 WP_328749008.1 alpha/beta hydrolase -
  OHT57_RS26525 (OHT57_26550) - 5771722..5772849 (+) 1128 WP_328749009.1 alpha/beta hydrolase -
  OHT57_RS26530 (OHT57_26555) - 5772890..5774110 (+) 1221 WP_328753334.1 acyltransferase -
  OHT57_RS26535 (OHT57_26560) - 5774103..5775473 (+) 1371 WP_328749011.1 sensor histidine kinase -
  OHT57_RS26540 (OHT57_26565) vraR 5775470..5776144 (+) 675 WP_328749012.1 response regulator transcription factor Regulator
  OHT57_RS26545 (OHT57_26570) - 5776271..5777635 (+) 1365 WP_328753335.1 histidine kinase -
  OHT57_RS26550 (OHT57_26575) vraR 5777632..5778297 (+) 666 WP_328749013.1 response regulator transcription factor Regulator
  OHT57_RS26555 (OHT57_26580) - 5778321..5778635 (-) 315 WP_328749014.1 hypothetical protein -
  OHT57_RS26560 (OHT57_26585) - 5778632..5778877 (-) 246 WP_328749015.1 hypothetical protein -
  OHT57_RS26565 (OHT57_26590) - 5779015..5779419 (-) 405 WP_328749016.1 ATP-binding protein -
  OHT57_RS26570 (OHT57_26595) - 5779638..5780492 (+) 855 WP_328749017.1 helix-turn-helix transcriptional regulator -
  OHT57_RS26575 (OHT57_26600) - 5780489..5780689 (+) 201 WP_328749018.1 DUF397 domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24226.97 Da        Isoelectric Point: 4.8631

>NTDB_id=652292 OHT57_RS26540 WP_328749012.1 5775470..5776144(+) (vraR) [Streptomyces sp. NBC_00285]
MTSSPIRVLIADDQQMVRQGFSVLLGAQPGIDVVGQAVDGLDAIAKVDELVPDVVLMDIRMPELGGIEATRRITGERPEI
KVLVLTTFDLDEYVYEALRAGASGFLLKDASAEQLAEAVRVVAAGDALLAPGITRRLIAEFSRLDDRPRAPLKSRVGELT
ERETEVLALIAQGLSNAEIAGRLVVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSRY

Nucleotide


Download         Length: 675 bp        

>NTDB_id=652292 OHT57_RS26540 WP_328749012.1 5775470..5776144(+) (vraR) [Streptomyces sp. NBC_00285]
ATGACGAGCAGCCCCATCCGTGTACTGATCGCCGACGACCAGCAGATGGTCCGGCAGGGCTTCAGCGTGCTGCTGGGCGC
GCAGCCCGGCATCGACGTGGTCGGACAGGCGGTCGACGGCCTGGACGCCATCGCCAAGGTCGACGAACTCGTCCCGGACG
TGGTCCTGATGGACATCCGCATGCCCGAGCTGGGCGGCATCGAGGCCACCCGCCGCATCACGGGCGAGCGCCCGGAGATC
AAGGTCCTCGTGCTGACCACCTTCGACCTCGACGAGTACGTCTACGAGGCGTTGCGGGCCGGGGCGTCCGGGTTCCTGCT
GAAGGACGCCTCCGCGGAGCAGCTCGCCGAGGCGGTGCGGGTGGTGGCGGCCGGGGACGCGCTGCTCGCGCCCGGTATCA
CCCGCCGTCTGATCGCCGAGTTCTCGCGCCTCGACGACCGGCCCCGGGCCCCGCTCAAGAGCCGGGTGGGGGAGCTCACC
GAGCGCGAGACGGAGGTCCTCGCCCTGATCGCGCAGGGACTGTCGAACGCGGAGATCGCCGGACGACTCGTGGTCGCCGA
GCAGACGGTGAAGACGCACGTGGGCCGCATCCTGGTGAAGCTGGGCCTCAGGGACCGGACCCAGGCGGCGGTGTTCGCGT
ACGAGTCGGGGCTGGTGCGGCCGTCGCGGTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-120)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.981

96.429

0.424
  degU Bacillus subtilis subsp. subtilis str. 168

40.889

100

0.411