Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT76_RS06730 Genome accession   NZ_CP108053
Coordinates   1490611..1491273 (+) Length   220 a.a.
NCBI ID   WP_328869832.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00287     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485611..1496273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT76_RS06705 (OHT76_06730) mug 1486716..1487267 (+) 552 WP_328876465.1 G/U mismatch-specific DNA glycosylase -
  OHT76_RS06710 (OHT76_06735) - 1487245..1487631 (-) 387 WP_328869828.1 hypothetical protein -
  OHT76_RS06715 (OHT76_06740) - 1487688..1488410 (-) 723 WP_328869829.1 ABC transporter permease -
  OHT76_RS06720 (OHT76_06745) - 1488412..1489332 (-) 921 WP_328869830.1 ATP-binding cassette domain-containing protein -
  OHT76_RS06725 (OHT76_06750) - 1489442..1490596 (+) 1155 WP_328869831.1 histidine kinase -
  OHT76_RS06730 (OHT76_06755) vraR 1490611..1491273 (+) 663 WP_328869832.1 response regulator transcription factor Regulator
  OHT76_RS06735 (OHT76_06760) - 1491395..1492552 (+) 1158 WP_328869833.1 ROK family transcriptional regulator -
  OHT76_RS06740 (OHT76_06765) - 1492616..1493377 (-) 762 WP_328869834.1 GntR family transcriptional regulator -
  OHT76_RS06745 (OHT76_06770) - 1493533..1494417 (-) 885 WP_328869835.1 RNA polymerase sigma-70 factor -
  OHT76_RS06750 (OHT76_06775) - 1494614..1495444 (+) 831 WP_328869836.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23441.01 Da        Isoelectric Point: 4.8752

>NTDB_id=652064 OHT76_RS06730 WP_328869832.1 1490611..1491273(+) (vraR) [Streptomyces sp. NBC_00287]
MPVTVLLVDDEPLVRAGLRAVLDAQPDIEVVGEAADGAAVIPLVRSLRPDVVAMDVRMPLLDGIEATRAVLRTVDEPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEHGENGGNPAARAAMERARLTER
EAEVLRLMARGLSNAEIAARLIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=652064 OHT76_RS06730 WP_328869832.1 1490611..1491273(+) (vraR) [Streptomyces sp. NBC_00287]
ATGCCGGTCACCGTTCTCCTTGTCGACGACGAACCCCTCGTACGCGCGGGCCTGCGGGCCGTCTTGGACGCGCAGCCGGA
CATCGAGGTCGTCGGGGAGGCCGCCGACGGGGCGGCGGTCATACCGCTGGTGCGGAGCCTGCGGCCGGACGTGGTCGCGA
TGGACGTACGGATGCCGCTGCTGGACGGGATCGAGGCCACGCGCGCGGTGCTGCGGACGGTCGACGAACCGCCGAAGATC
CTCGTGGTGACGACGTTCGAGAACGACGAGTACGTCTATGAGGCATTGCGGGCCGGGGCCGACGGGTTTCTGCTGAAGCG
GGCCCGGCCCGCCGAGATCGTGCACGCGGTCCGGCTGGTCGCGGAGGGCGAGTCGCTGCTGTTCCCGGCGTCGGTGCGGC
AGCTCGCCGCCGAGCACGGCGAGAACGGCGGCAACCCCGCCGCGCGCGCCGCGATGGAGCGGGCCCGGCTGACCGAGCGG
GAGGCGGAAGTGCTGCGGCTGATGGCGCGCGGGCTGTCGAACGCGGAGATCGCGGCCCGGCTGATCGTCGGCACGGAGAC
GGTGAAGTCGCATGTGAGCGCCGTACTGGCGAAGCTGGGAGCCCGGGACCGTACGCAGGCGGTGATCGCGGCGTACGAGT
CGGGGTTCGTGGCGCCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.284

99.091

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.382