Detailed information NTG0650780

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: OHT74_RS25470
• Genome accession: NZ_CP107983
• Coordinates: 5565326..5566612 (+)
• Length: 428 a.a.
• NCBI ID: WP_030159377.1
• Uniprot ID: A0A5J6JHR3
• Organism: Streptomyces sp. NBC_00354
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5560326..5571612

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHT74_RS25440 (OHT74_25465)	-	5560573..5561022 (+)	450	WP_328621496.1	hypothetical protein	-
OHT74_RS25455 (OHT74_25480)	tig	5562071..5563474 (+)	1404	WP_266667047.1	trigger factor	-
OHT74_RS25460 (OHT74_25485)	-	5563798..5564415 (+)	618	WP_266667049.1	ATP-dependent Clp protease proteolytic subunit	-
OHT74_RS25465 (OHT74_25490)	clpP	5564501..5565172 (+)	672	WP_323139594.1	ATP-dependent Clp protease proteolytic subunit	Regulator
OHT74_RS25470 (OHT74_25495)	clpX	5565326..5566612 (+)	1287	WP_030159377.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
OHT74_RS25475 (OHT74_25500)	-	5566780..5567055 (+)	276	WP_328621497.1	hypothetical protein	-
OHT74_RS25480 (OHT74_25505)	-	5567108..5568043 (-)	936	WP_328621498.1	hypothetical protein	-
OHT74_RS25485 (OHT74_25510)	-	5568173..5570794 (+)	2622	WP_328621499.1	valine--tRNA ligase	-

Sequence

Protein

• Length: 428 a.a.
• Molecular weight: 46925.81 Da
• Isoelectric Point: 4.7271

>NTDB_id=650780 OHT74_RS25470 WP_030159377.1 5565326..5566612(+) (clpX) [Streptomyces sp. NBC_00354]
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLESYVVGQEP
AKKALSVAVYNHYKRVQAGENGGAQGRDDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGED
VENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQ
IDTTNVLFIVGGAFAGLEKIIESRAGAKGIGFGATIRSKREIEASDQFQEVMPEDLVKFGMIPEFIGRLPVITSVHNLDR
EALLQILVEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLMSVMYEVPSRKDVARVVIT
SDVVRSNVNPTLVPRIVPKDQGPQEKSA

Nucleotide

• Length: 1287 bp

>NTDB_id=650780 OHT74_RS25470 WP_030159377.1 5565326..5566612(+) (clpX) [Streptomyces sp. NBC_00354]
GTGGCACGCATCGGTGACGGCGGCGACCTGCTCAAGTGCTCGTTCTGCGGAAAGAGCCAGAAGCAGGTGAAGAAGCTCAT
CGCAGGACCCGGTGTGTACATCTGCGACGAGTGCATCGACCTCTGCAACGAGATCATCGAGGAGGAGCTCGCCGAGACCT
CCGAGGTCCGGTGGGAGGAACTCCCCAAGCCTCGTGAGATCTACGAGTTCCTGGAGAGCTACGTCGTCGGCCAGGAGCCG
GCGAAGAAGGCCCTCTCGGTGGCGGTCTACAACCACTACAAGCGCGTCCAGGCCGGCGAGAACGGCGGTGCGCAGGGCCG
GGACGACGCGATCGAGCTCGCGAAGTCCAACATCCTGCTGCTGGGCCCGACGGGCTCGGGCAAGACGCTCCTCGCCCAGA
CGCTCGCGCGCATGCTCAACGTCCCGTTCGCCATCGCCGACGCGACGGCGCTGACGGAGGCCGGGTACGTCGGCGAGGAC
GTCGAGAACATCCTGCTCAAGCTGATCCAGGCGGCCGACTACGACGTCAAGAAGGCCGAGACCGGGATCATCTACATCGA
CGAGATCGACAAGGTCGCCCGCAAGAGCGAGAACCCGTCGATCACGCGCGACGTGAGCGGCGAGGGCGTGCAGCAGGCCC
TGCTGAAGATCCTCGAGGGCACGACGGCCTCGGTCCCGCCGCAGGGCGGCCGCAAGCACCCGCACCAGGAGTTCATCCAG
ATCGACACGACGAACGTGCTCTTCATCGTGGGCGGCGCCTTCGCCGGCCTCGAGAAGATCATCGAGTCGCGTGCGGGCGC
CAAGGGCATCGGCTTCGGGGCGACGATCCGCTCGAAGCGCGAGATCGAGGCGAGCGACCAGTTCCAGGAGGTCATGCCGG
AGGACCTGGTGAAGTTCGGGATGATCCCGGAGTTCATCGGCCGTCTGCCCGTGATCACCTCGGTCCACAACCTGGACCGC
GAGGCGCTGCTGCAGATCCTGGTGGAGCCGCGGAACGCGCTGGTGAAGCAGTACCAGCGGCTGTTCGAACTCGACGGCGT
CGAGCTGGACTTCGAGCGCGAGGCGCTGGAAGCCATCGCGGACCAGGCGATCCTCCGCCAGACCGGCGCGCGCGGCCTGC
GCGCCATCATGGAAGAGGTCCTGATGTCGGTGATGTACGAGGTCCCGTCCCGCAAGGACGTGGCCCGCGTGGTCATCACC
TCGGACGTCGTCCGCTCGAACGTGAACCCGACGCTGGTCCCCCGCATCGTCCCGAAGGACCAGGGCCCGCAGGAGAAGTC
GGCGTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (115-312)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (318-395)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

3D structure

• AlphaFold DB: A0A5J6JHR3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	63.682	93.925	0.598
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.015	96.028	0.519