Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT74_RS18190 Genome accession   NZ_CP107983
Coordinates   4036417..4037076 (+) Length   219 a.a.
NCBI ID   WP_266665461.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4031417..4042076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT74_RS18170 (OHT74_18195) - 4031771..4032982 (+) 1212 WP_328620766.1 acyltransferase -
  OHT74_RS18175 (OHT74_18200) - 4032993..4034294 (+) 1302 WP_328620767.1 sensor histidine kinase -
  OHT74_RS18180 (OHT74_18205) vraR 4034291..4034971 (+) 681 WP_266996099.1 response regulator transcription factor Regulator
  OHT74_RS18185 (OHT74_18210) - 4035059..4036420 (+) 1362 WP_328620768.1 histidine kinase -
  OHT74_RS18190 (OHT74_18215) vraR 4036417..4037076 (+) 660 WP_266665461.1 response regulator transcription factor Regulator
  OHT74_RS18195 (OHT74_18220) - 4037153..4038349 (+) 1197 WP_266665463.1 cytochrome P450 -
  OHT74_RS18200 (OHT74_18225) - 4038554..4040128 (-) 1575 WP_328620769.1 ABC transporter permease -
  OHT74_RS18205 (OHT74_18230) - 4040125..4041141 (-) 1017 WP_328620770.1 ABC transporter ATP-binding protein -
  OHT74_RS18210 (OHT74_18235) - 4041217..4041723 (+) 507 WP_328623339.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23586.39 Da        Isoelectric Point: 4.5518

>NTDB_id=650764 OHT74_RS18190 WP_266665461.1 4036417..4037076(+) (vraR) [Streptomyces sp. NBC_00354]
MTIRVLIVDDQMMVREGFSVLLNAMDGIEVVGEAVDGREAIAQVAALRPDVVLMDIRMPVMNGLEATREIVASDTDAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTKRLILEFSKLSTPPKVADPAGVGELTERE
TEVLVLIAQGLSNAEIADRLIVAESTIKTHVSRILVKLGLRDRTQAAVFAYETRLVTPA

Nucleotide


Download         Length: 660 bp        

>NTDB_id=650764 OHT74_RS18190 WP_266665461.1 4036417..4037076(+) (vraR) [Streptomyces sp. NBC_00354]
ATGACGATCAGGGTCCTCATCGTCGACGACCAGATGATGGTCCGGGAGGGCTTCTCCGTCCTGCTGAACGCGATGGACGG
CATCGAGGTGGTCGGCGAGGCGGTGGACGGCCGCGAAGCCATCGCCCAAGTGGCGGCGCTGCGGCCGGACGTGGTGCTGA
TGGACATCCGGATGCCGGTGATGAACGGGCTGGAGGCGACACGGGAGATCGTCGCCTCCGACACGGACGCGAAGGTGCTG
GTCCTGACGACCTTCGACCTCGACGAGTACGTGTACCAGGCCCTGCGGGCCGGGGCCTCCGGGTTCCTGCTCAAGGACGC
CTCGGCGCGGCAGCTGGCCGACGGGGTGCGGGTGGTGGCGTCCGGTGAGGCGCTGCTGGCGCCCACGGTCACCAAGCGGC
TGATCCTGGAGTTCTCGAAGCTCTCGACCCCGCCGAAGGTCGCGGATCCGGCCGGGGTCGGGGAGCTGACGGAGCGGGAG
ACGGAGGTGCTGGTGCTGATCGCGCAGGGGCTGTCCAACGCGGAGATAGCGGACCGGCTCATCGTCGCGGAGTCCACGAT
CAAGACGCATGTGAGCCGGATCCTGGTGAAGCTGGGCCTGCGCGACCGCACTCAGGCCGCGGTCTTCGCCTACGAGACCC
GTCTGGTGACGCCGGCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.907

98.63

0.443
  degU Bacillus subtilis subsp. subtilis str. 168

41.333

100

0.425