Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT74_RS18180 Genome accession   NZ_CP107983
Coordinates   4034291..4034971 (+) Length   226 a.a.
NCBI ID   WP_266996099.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4029291..4039971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT74_RS18155 (OHT74_18180) - 4029578..4029979 (+) 402 WP_328620764.1 nuclear transport factor 2 family protein -
  OHT74_RS18160 (OHT74_18185) - 4030019..4030534 (-) 516 WP_328620765.1 diadenosine tetraphosphate hydrolase -
  OHT74_RS18165 (OHT74_18190) - 4030765..4031778 (+) 1014 WP_266665452.1 alpha/beta hydrolase -
  OHT74_RS18170 (OHT74_18195) - 4031771..4032982 (+) 1212 WP_328620766.1 acyltransferase -
  OHT74_RS18175 (OHT74_18200) - 4032993..4034294 (+) 1302 WP_328620767.1 sensor histidine kinase -
  OHT74_RS18180 (OHT74_18205) vraR 4034291..4034971 (+) 681 WP_266996099.1 response regulator transcription factor Regulator
  OHT74_RS18185 (OHT74_18210) - 4035059..4036420 (+) 1362 WP_328620768.1 histidine kinase -
  OHT74_RS18190 (OHT74_18215) vraR 4036417..4037076 (+) 660 WP_266665461.1 response regulator transcription factor Regulator
  OHT74_RS18195 (OHT74_18220) - 4037153..4038349 (+) 1197 WP_266665463.1 cytochrome P450 -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 23999.67 Da        Isoelectric Point: 4.5295

>NTDB_id=650763 OHT74_RS18180 WP_266996099.1 4034291..4034971(+) (vraR) [Streptomyces sp. NBC_00354]
MSTPADPIRVMIADDQMMVRQGFTVLLNAQPDIEVVGQAVDGADAVAKVGELGPDVVLMDIRMPGMGGIEATSVITAAPD
ATVKVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVVAAGEALLSPNITKRLITEFSRMGAPRAPSKARIDE
LTERETEVLSLIAQGLSNAEIAGHLVVAEQTVKTHVGRILVKLGLRDRTQAAVFAYETGLIRPTGY

Nucleotide


Download         Length: 681 bp        

>NTDB_id=650763 OHT74_RS18180 WP_266996099.1 4034291..4034971(+) (vraR) [Streptomyces sp. NBC_00354]
ATGAGCACTCCGGCCGACCCGATCAGGGTGATGATCGCCGACGACCAGATGATGGTCCGGCAGGGCTTCACCGTCCTCCT
CAACGCCCAGCCCGACATCGAGGTCGTCGGCCAGGCCGTGGACGGCGCCGACGCGGTGGCGAAGGTCGGCGAACTCGGCC
CGGACGTGGTCCTGATGGACATCCGCATGCCCGGGATGGGCGGCATCGAGGCCACCTCCGTCATCACGGCCGCCCCGGAC
GCCACGGTCAAGGTGCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACGAGGCGCTGCGCGCGGGGGCTTCCGG
CTTCCTCCTGAAGGACGCATCGGCCGACCAGCTCGCGGAGGCGGTCCGGGTGGTGGCGGCCGGCGAGGCGCTGCTCTCGC
CGAACATCACCAAGCGGCTGATCACGGAGTTCTCCCGGATGGGGGCGCCGCGTGCGCCCTCGAAGGCGCGGATCGACGAG
CTGACCGAGCGGGAGACCGAGGTGCTGTCGCTGATCGCCCAGGGCCTGTCCAACGCGGAGATCGCCGGGCACCTGGTCGT
GGCCGAGCAGACCGTGAAGACCCATGTGGGGCGGATCCTGGTGAAACTGGGCCTGCGGGACCGCACCCAGGCCGCGGTGT
TCGCGTACGAGACGGGGCTGATCCGTCCGACGGGCTACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-215)

Response regulator receiver domain (Response_reg)

(10-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.24

96.018

0.425
  degU Bacillus subtilis subsp. subtilis str. 168

40.889

99.558

0.407