Detailed information NTG0649393

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: L2Z42_RS17470
• Genome accession: NZ_CP091335
• Coordinates: 3620917..3623349 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472702.1
• Uniprot ID: A0A1E3MCU2
• Organism: Acinetobacter baumannii strain ATCC17978-VUB
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	3615887..3628022	3620917..3623349	within	0

Gene organization within MGE regions

Location: 3615887..3628022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L2Z42_RS17440 (L2Z42_17440)	-	3615887..3616033 (-)	147	WP_000691794.1	hypothetical protein	-
L2Z42_RS17445 (L2Z42_17445)	-	3616067..3617008 (-)	942	WP_000795877.1	hypothetical protein	-
L2Z42_RS17450 (L2Z42_17450)	-	3617265..3617750 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
L2Z42_RS17455 (L2Z42_17455)	-	3617761..3618669 (+)	909	WP_001140078.1	EamA family transporter	-
L2Z42_RS18780	-	3618699..3618897 (-)	199	Protein_3389	hypothetical protein	-
L2Z42_RS17460 (L2Z42_17460)	-	3618917..3620152 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
L2Z42_RS17465 (L2Z42_17465)	lolD	3620145..3620831 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
L2Z42_RS17470 (L2Z42_17470)	comA/comEC	3620917..3623349 (+)	2433	WP_000472702.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L2Z42_RS17475 (L2Z42_17475)	-	3623302..3624285 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
L2Z42_RS17480 (L2Z42_17480)	sppA	3624418..3625434 (+)	1017	WP_001286612.1	signal peptide peptidase SppA	-
L2Z42_RS17485 (L2Z42_17485)	-	3625453..3626262 (+)	810	WP_000114071.1	alpha/beta hydrolase	-
L2Z42_RS17490 (L2Z42_17490)	purN	3626326..3626955 (-)	630	WP_000975525.1	phosphoribosylglycinamide formyltransferase	-
L2Z42_RS17495 (L2Z42_17495)	purM	3626952..3628022 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92486.72 Da
• Isoelectric Point: 8.5374

>NTDB_id=649393 L2Z42_RS17470 WP_000472702.1 3620917..3623349(+) (comA/comEC) [Acinetobacter baumannii strain ATCC17978-VUB]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINHLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIVSSFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQILMAVPCCLGVLIYTA
FVGFEIPALRTLLSVFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVFSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=649393 L2Z42_RS17470 WP_000472702.1 3620917..3623349(+) (comA/comEC) [Acinetobacter baumannii strain ATCC17978-VUB]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCATTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCATTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGCCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTGTGTCTAGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGATTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGTATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGTTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTTTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTAGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A1E3MCU2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.148	100	0.981
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504