Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU74_RS19495 Genome accession   NZ_CP107907
Coordinates   4174845..4175546 (-) Length   233 a.a.
NCBI ID   WP_371617103.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00454     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4169845..4180546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU74_RS19475 (OHU74_19480) - 4169974..4170900 (+) 927 WP_371617099.1 ATP-binding cassette domain-containing protein -
  OHU74_RS19480 (OHU74_19485) - 4170897..4172687 (+) 1791 WP_371617100.1 ABC transporter permease -
  OHU74_RS19485 (OHU74_19490) vraR 4172777..4173436 (-) 660 WP_371617101.1 response regulator Regulator
  OHU74_RS19490 (OHU74_19495) - 4173433..4174755 (-) 1323 WP_371617102.1 sensor histidine kinase -
  OHU74_RS19495 (OHU74_19500) vraR 4174845..4175546 (-) 702 WP_371617103.1 response regulator Regulator
  OHU74_RS19500 (OHU74_19505) - 4175543..4176931 (-) 1389 WP_371617104.1 sensor histidine kinase -
  OHU74_RS19505 (OHU74_19510) - 4176942..4178231 (-) 1290 WP_371617105.1 acyltransferase -
  OHU74_RS19510 (OHU74_19515) - 4178218..4179276 (-) 1059 WP_371617106.1 alpha/beta hydrolase -
  OHU74_RS19515 (OHU74_19520) - 4179505..4179906 (-) 402 WP_330297702.1 nuclear transport factor 2 family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 24575.55 Da        Isoelectric Point: 4.6888

>NTDB_id=648701 OHU74_RS19495 WP_371617103.1 4174845..4175546(-) (vraR) [Streptomyces sp. NBC_00454]
MTAPITTGPLATAPIKVMIVDDQMMVRQGFTVLLNAQPDIEVVGQAVDGAEAVAKVCELAPDVVLMDIRMPGMGGIEATG
LITGAPGATVKVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVIAAGDALLAPNITKRLITEFSRLGAPRGP
SKARIEELTERETEVLSLVAQGLSNAEIAGHLVLAEQTVKTHVGRILVKLGLRDRTQAAVFAYETGLIRPTGY

Nucleotide


Download         Length: 702 bp        

>NTDB_id=648701 OHU74_RS19495 WP_371617103.1 4174845..4175546(-) (vraR) [Streptomyces sp. NBC_00454]
ATGACTGCCCCGATCACGACTGGACCGCTCGCGACCGCCCCGATCAAGGTGATGATCGTCGACGACCAGATGATGGTCCG
CCAGGGCTTCACCGTGCTCCTCAACGCCCAGCCCGACATCGAGGTCGTCGGCCAGGCCGTCGACGGCGCCGAGGCCGTGG
CGAAGGTCTGCGAACTGGCGCCGGACGTGGTCCTGATGGACATCCGCATGCCCGGCATGGGCGGGATCGAGGCCACGGGC
CTGATCACCGGCGCCCCCGGGGCCACGGTGAAGGTGCTCGTGCTGACCACCTTCGACCTCGACGAGTACGTCTACGAGGC
GCTGCGCGCCGGAGCCTCGGGGTTCCTCCTCAAGGACGCCTCGGCGGACCAGCTGGCCGAGGCGGTCCGGGTGATCGCGG
CCGGTGACGCGCTCCTCGCGCCGAACATCACCAAGCGGCTGATCACCGAGTTCTCCCGGCTGGGAGCTCCGCGGGGGCCT
TCGAAGGCGCGGATCGAGGAGCTGACGGAGCGGGAGACGGAGGTGCTGTCGCTGGTCGCCCAGGGCCTTTCGAACGCGGA
GATCGCCGGGCATCTGGTCCTGGCCGAGCAGACCGTGAAGACGCATGTGGGGCGGATCCTGGTGAAGCTGGGTCTGCGGG
ACCGCACGCAGGCCGCGGTGTTCGCTTACGAAACGGGTCTGATCCGTCCGACGGGCTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-130)

Bacterial regulatory proteins, luxR family (GerE)

(168-222)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.444

92.704

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

41.778

96.567

0.403