Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU74_RS19485 Genome accession   NZ_CP107907
Coordinates   4172777..4173436 (-) Length   219 a.a.
NCBI ID   WP_371617101.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00454     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4167777..4178436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU74_RS19460 (OHU74_19465) - 4167891..4168577 (-) 687 WP_371617096.1 alpha/beta hydrolase -
  OHU74_RS19465 (OHU74_19470) - 4168663..4169385 (+) 723 WP_371617097.1 HAD family hydrolase -
  OHU74_RS19470 (OHU74_19475) - 4169398..4169898 (-) 501 WP_371617098.1 GbsR/MarR family transcriptional regulator -
  OHU74_RS19475 (OHU74_19480) - 4169974..4170900 (+) 927 WP_371617099.1 ATP-binding cassette domain-containing protein -
  OHU74_RS19480 (OHU74_19485) - 4170897..4172687 (+) 1791 WP_371617100.1 ABC transporter permease -
  OHU74_RS19485 (OHU74_19490) vraR 4172777..4173436 (-) 660 WP_371617101.1 response regulator Regulator
  OHU74_RS19490 (OHU74_19495) - 4173433..4174755 (-) 1323 WP_371617102.1 sensor histidine kinase -
  OHU74_RS19495 (OHU74_19500) vraR 4174845..4175546 (-) 702 WP_371617103.1 response regulator Regulator
  OHU74_RS19500 (OHU74_19505) - 4175543..4176931 (-) 1389 WP_371617104.1 sensor histidine kinase -
  OHU74_RS19505 (OHU74_19510) - 4176942..4178231 (-) 1290 WP_371617105.1 acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23555.29 Da        Isoelectric Point: 4.5497

>NTDB_id=648700 OHU74_RS19485 WP_371617101.1 4172777..4173436(-) (vraR) [Streptomyces sp. NBC_00454]
MTIRVLIVDDQMMVREGFSVLLNAMEGIEVVGEAVNGREAIAQVAALKPDVVLMDIRMPEMNGLEATRAIVAADADAKVL
VLTTFDLDEYVYQALQAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTRRLITEFAKLSGTRVFTSSEGTGELTERE
TEVLVLIAQGLSNAEIADRLIIAESTIKTHVSRILVKLGLRDRTQAAVFAYETRLVIPA

Nucleotide


Download         Length: 660 bp        

>NTDB_id=648700 OHU74_RS19485 WP_371617101.1 4172777..4173436(-) (vraR) [Streptomyces sp. NBC_00454]
ATGACGATCCGGGTGCTGATCGTCGACGACCAGATGATGGTCCGGGAGGGGTTCTCCGTCCTCCTGAACGCGATGGAGGG
CATCGAGGTGGTCGGGGAGGCGGTGAACGGACGCGAGGCCATCGCGCAGGTGGCGGCGCTGAAGCCGGACGTGGTCCTGA
TGGACATCCGGATGCCGGAGATGAACGGCCTGGAGGCGACCCGGGCGATCGTGGCCGCCGACGCGGACGCGAAGGTGCTG
GTCCTGACGACCTTCGACCTCGACGAGTACGTGTACCAGGCCCTGCAGGCCGGGGCCTCCGGGTTCCTCCTCAAGGACGC
CTCCGCCCGGCAACTGGCCGATGGGGTACGGGTGGTGGCCGCCGGGGAGGCGCTGCTGGCCCCCTCGGTGACCAGGCGGC
TGATCACCGAGTTCGCGAAGCTCTCGGGCACCCGGGTGTTCACGAGCAGCGAGGGGACCGGGGAGTTGACGGAGCGGGAG
ACGGAGGTGCTGGTGCTGATCGCGCAGGGACTGTCCAATGCGGAGATAGCCGACCGGCTGATCATCGCCGAGTCCACGAT
CAAGACCCACGTGAGCCGGATCCTGGTGAAGCTGGGCCTGCGGGACCGCACACAGGCCGCGGTGTTCGCCTACGAGACCC
GGCTGGTGATCCCGGCCTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.296

98.63

0.457
  degU Bacillus subtilis subsp. subtilis str. 168

42.152

100

0.429