Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG828_RS23315 Genome accession   NZ_CP107905
Coordinates   5136053..5136718 (-) Length   221 a.a.
NCBI ID   WP_210580566.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00457     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5131053..5141718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG828_RS23280 (OG828_23255) - 5131473..5131658 (-) 186 WP_328439467.1 DUF397 domain-containing protein -
  OG828_RS23285 (OG828_23260) - 5131658..5132509 (-) 852 WP_328439468.1 helix-turn-helix transcriptional regulator -
  OG828_RS23290 (OG828_23265) - 5132737..5133144 (+) 408 WP_328439469.1 ATP-binding protein -
  OG828_RS23295 (OG828_23270) - 5133174..5133311 (-) 138 WP_328439470.1 hypothetical protein -
  OG828_RS23300 (OG828_23275) - 5133560..5134411 (+) 852 WP_328439471.1 GntR family transcriptional regulator -
  OG828_RS23305 (OG828_23280) - 5134438..5135265 (-) 828 WP_328502210.1 class I SAM-dependent methyltransferase -
  OG828_RS23310 (OG828_23285) - 5135338..5135940 (+) 603 WP_328439473.1 TetR/AcrR family transcriptional regulator -
  OG828_RS23315 (OG828_23290) vraR 5136053..5136718 (-) 666 WP_210580566.1 response regulator transcription factor Regulator
  OG828_RS23320 (OG828_23295) - 5136715..5138055 (-) 1341 WP_328502211.1 histidine kinase -
  OG828_RS23325 (OG828_23300) vraR 5138180..5138854 (-) 675 WP_328502212.1 response regulator transcription factor Regulator
  OG828_RS23330 (OG828_23305) - 5138851..5140191 (-) 1341 WP_328504921.1 sensor histidine kinase -
  OG828_RS23335 (OG828_23310) - 5140331..5141518 (-) 1188 WP_328504922.1 acyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23949.60 Da        Isoelectric Point: 4.6025

>NTDB_id=648601 OG828_RS23315 WP_210580566.1 5136053..5136718(-) (vraR) [Streptomyces sp. NBC_00457]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVDRVRELSPDVVLMDIRMPELNGIEATREIVAADDAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTKRLITEFSKLSEAPRAMSTAHAAYGELTE
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=648601 OG828_RS23315 WP_210580566.1 5136053..5136718(-) (vraR) [Streptomyces sp. NBC_00457]
ATGACCATCCGCGTGCTGATCGCGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCCGTCAACGGCCGGGAGGCGGTGGACCGCGTCCGCGAACTGTCCCCGGACGTCGTGCTGA
TGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTCGCGGCGGACGACGCGGCGAAGGTGCTG
GTGCTGACCACCTTCGACCTGGACGAATACGTCTACCAGGCGCTGCGGGCAGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTCGCCGACGGCGTACGGGTGGTGGCGTCCGGTGAGGCCCTCCTCGCCCCCTCCGTCACCAAGCGCC
TGATCACCGAGTTCTCCAAACTGTCCGAGGCCCCGCGCGCCATGTCCACCGCCCACGCGGCGTACGGCGAACTGACCGAA
CGGGAGACGGAGGTCCTGGTCCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGAGCGCCTGGTGGTGGCGGAGTC
GACCATCAAGACCCACGTCAGCCGGATCCTGGTAAAGCTCGGCCTCAGGGACCGCACGCAGGCGGCGGTCTTCGCGTACG
AGGCACGGCTGGTGACGCCGGGTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.495

98.643

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421