Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KB224_RS03855 Genome accession   NZ_CP091006
Coordinates   832657..833373 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain R10C     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 827657..838373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KB224_RS03840 (KB224_03840) - 828937..829890 (+) 954 WP_002470302.1 LacI family DNA-binding transcriptional regulator -
  KB224_RS03845 (KB224_03845) - 830151..831623 (+) 1473 WP_002470315.1 sucrose-6-phosphate hydrolase -
  KB224_RS03850 (KB224_03850) - 831630..832589 (+) 960 WP_002468351.1 carbohydrate kinase family protein -
  KB224_RS03855 (KB224_03855) agrA 832657..833373 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  KB224_RS03860 (KB224_03860) agrC 833390..834679 (-) 1290 WP_002495230.1 quorum-sensing sensor histidine kinase AgrC -
  KB224_RS03865 (KB224_03865) agrD 834704..834844 (-) 141 WP_002468352.1 cyclic lactone autoinducer peptide AgrD -
  KB224_RS03870 (KB224_03870) - 834850..835413 (-) 564 WP_002470294.1 accessory gene regulator AgrB -
  KB224_RS03875 (KB224_03875) hld 835730..835807 (+) 78 WP_002494082.1 delta-hemolysin -
  KB224_RS03880 (KB224_03880) - 836188..836973 (-) 786 WP_002470342.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=647092 KB224_RS03855 WP_001829999.1 832657..833373(-) (agrA) [Staphylococcus epidermidis strain R10C]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=647092 KB224_RS03855 WP_001829999.1 832657..833373(-) (agrA) [Staphylococcus epidermidis strain R10C]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTCGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGGCTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAAAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374