Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN73_RS21375 Genome accession   NZ_CP107839
Coordinates   4583266..4583931 (-) Length   221 a.a.
NCBI ID   WP_266518618.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00519     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4578266..4588931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN73_RS21350 (OHN73_21240) - 4578469..4578887 (+) 419 Protein_4242 ATP-binding protein -
  OHN73_RS21355 (OHN73_21245) - 4578884..4580047 (+) 1164 WP_266518626.1 sensor histidine kinase -
  OHN73_RS21360 (OHN73_21250) - 4580044..4580703 (+) 660 WP_266518624.1 response regulator transcription factor -
  OHN73_RS21365 (OHN73_21255) - 4580881..4581519 (+) 639 WP_266518622.1 GPP34 family phosphoprotein -
  OHN73_RS21370 (OHN73_21260) - 4581604..4583208 (+) 1605 WP_266518620.1 carboxylesterase/lipase family protein -
  OHN73_RS21375 (OHN73_21265) vraR 4583266..4583931 (-) 666 WP_266518618.1 response regulator transcription factor Regulator
  OHN73_RS21380 (OHN73_21270) - 4583928..4585295 (-) 1368 WP_266518616.1 sensor histidine kinase -
  OHN73_RS21385 (OHN73_21275) vraR 4585430..4586110 (-) 681 WP_266518613.1 response regulator transcription factor Regulator
  OHN73_RS21390 (OHN73_21280) - 4586107..4587615 (-) 1509 WP_406321109.1 sensor histidine kinase -
  OHN73_RS21395 (OHN73_21285) - 4587626..4588864 (-) 1239 WP_406321110.1 acyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23941.68 Da        Isoelectric Point: 4.7252

>NTDB_id=646829 OHN73_RS21375 WP_266518618.1 4583266..4583931(-) (vraR) [Streptomyces sp. NBC_00519]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVDRVRELAPDVVLMDIRMPEMNGIEATREIVAADSPSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTKRLITEFSKLSTSPRLMQSAQAAYGDLTE
RETEVLVLIAQGLSNAEIAGRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=646829 OHN73_RS21375 WP_266518618.1 4583266..4583931(-) (vraR) [Streptomyces sp. NBC_00519]
ATGACCATCCGCGTCCTGATCGCGGACGATCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTGGGCGAGGCGGTCAACGGCCGCGAGGCGGTCGACCGCGTCCGTGAACTGGCCCCCGACGTGGTCCTGA
TGGACATCCGCATGCCCGAAATGAACGGCATCGAGGCGACCCGGGAGATCGTGGCCGCCGACAGCCCGTCGAAGGTCCTC
GTCCTCACGACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCGGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTCGCGGACGGCGTAAGGGTGGTGGCCTCCGGTGAGGCACTCCTCGCACCGACCGTCACCAAGCGGC
TGATCACGGAGTTCTCGAAGCTGTCCACGTCCCCCCGCCTCATGCAGTCCGCCCAGGCGGCGTACGGCGATCTGACCGAG
CGCGAGACGGAGGTCCTGGTCCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGGGCGCCTCGTGGTCGCCGAGTC
GACGATCAAGACCCACGTCAGCCGCATCCTGGTCAAGCTGGGCCTCAGGGACCGCACACAGGCGGCGGTGTTCGCGTACG
AGGCGCGACTGGTGACACCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.662

99.095

0.452
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421