Detailed information NTG0646583

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHS33_RS16260
• Genome accession: NZ_CP107819
• Coordinates: 3748661..3749785 (+)
• Length: 374 a.a.
• NCBI ID: WP_330331123.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00536
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3743661..3754785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS33_RS16245 (OHS33_16240)	-	3744291..3745139 (+)	849	WP_330331120.1	hypothetical protein	-
OHS33_RS16250 (OHS33_16245)	-	3745144..3746916 (-)	1773	WP_330331121.1	hypothetical protein	-
OHS33_RS16255 (OHS33_16250)	radA	3747074..3748483 (+)	1410	WP_330331122.1	DNA repair protein RadA	Machinery gene
OHS33_RS16260 (OHS33_16255)	disA	3748661..3749785 (+)	1125	WP_330331123.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHS33_RS16265 (OHS33_16260)	-	3749991..3750800 (-)	810	WP_330331124.1	hypothetical protein	-
OHS33_RS16270 (OHS33_16265)	-	3750981..3751592 (+)	612	WP_330331125.1	phosphatase PAP2 family protein	-
OHS33_RS16275 (OHS33_16270)	-	3751615..3752574 (+)	960	WP_330331126.1	A/G-specific adenine glycosylase	-
OHS33_RS16280 (OHS33_16275)	-	3752771..3753331 (+)	561	WP_330331127.1	SigE family RNA polymerase sigma factor	-
OHS33_RS16285 (OHS33_16280)	-	3753364..3753981 (+)	618	WP_330331128.1	hypothetical protein	-
OHS33_RS16290 (OHS33_16285)	cseB	3754024..3754734 (+)	711	WP_330331129.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40400.22 Da
• Isoelectric Point: 4.9472

>NTDB_id=646583 OHS33_RS16260 WP_330331123.1 3748661..3749785(+) (disA) [Streptomyces sp. NBC_00536]
MAAKDGAAASGKSGAGSKQEALMRASLSAVAPGQQLRDGLERILRGNTGGLIVLGMDKSVESMCTGGFVLDVEFTATRLR
ELCKLDGALIVDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCNFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVDEALAELDSLTHAELLELATVARGLGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=646583 OHS33_RS16260 WP_330331123.1 3748661..3749785(+) (disA) [Streptomyces sp. NBC_00536]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCCGGCGCAGGCAGCAAGCAGGAGGCCCTCATGCGGGCCTCGCT
GAGCGCGGTCGCACCTGGTCAGCAGCTGCGTGACGGCCTGGAGCGGATCCTGCGCGGCAACACGGGCGGTCTGATCGTTC
TCGGTATGGACAAGAGCGTCGAGTCGATGTGCACCGGCGGATTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGGGCGCTCATCGTCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGCTGGTACC
GGACGCGTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGCGTCTCCAAGCAGTGCAACTTCCCGG
TCGTCTCGGTCTCGCAGTCGATGCGGCTGATCGCGCTGTACGTCGACGGCGAGCGGCGCGTGCTGGAGGAGTCCGGGGCG
ATCCTGTCCCGGGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCACGGCGGTCGCGCAGCGGCTGGAGATGGTCCGGCGGATCG
CGACCGAGATCGCCGAATACGTGGTGGAACTCGGCACCGACGGGCGGCTGCTGTCGCTCCAGCTGGACGAGCTGACCGTC
GGGATCGAGCAGGAGCGCGAGCTGGTCATCCGGGACTACGTGCCCGAGCCGACGGCGAAGCGTTCCCGCACGGTGGACGA
GGCGCTGGCCGAGCTGGACTCCCTCACCCACGCGGAGCTGCTGGAACTGGCGACGGTGGCGCGGGGGCTGGGGTACACGG
GCTCGCCCGAAACCCTCGACTCGGCGGTGTCGCCCCGCGGGTACCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGGCC
ATCATCGAGCGGCTCGTGGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGATCTGCAGACCGTCGA
CGGCGTCGGCGAGGCGCGGGCGCGGTCGGTGCGGGAAGGGCTGTCGCGGCTGGCGGAGTCTTCGATCCTGGAGCGCTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.429	96.524	0.438