Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG266_RS35105 Genome accession   NZ_CP107799
Coordinates   7964202..7964843 (+) Length   213 a.a.
NCBI ID   WP_266466379.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00554 strain NBC 00554     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7959202..7969843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG266_RS35085 (OG266_35060) - 7960048..7960797 (-) 750 WP_371550637.1 transglycosylase SLT domain-containing protein -
  OG266_RS35090 (OG266_35065) - 7961097..7962182 (-) 1086 WP_371550638.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG266_RS35095 (OG266_35070) - 7962179..7962874 (-) 696 WP_371550640.1 SDR family NAD(P)-dependent oxidoreductase -
  OG266_RS35100 (OG266_35075) - 7963064..7964209 (+) 1146 WP_266466377.1 GAF domain-containing sensor histidine kinase -
  OG266_RS35105 (OG266_35080) vraR 7964202..7964843 (+) 642 WP_266466379.1 response regulator transcription factor Regulator
  OG266_RS35110 (OG266_35085) chpE 7964988..7965236 (+) 249 WP_266466382.1 chaplin ChpE -
  OG266_RS35115 (OG266_35090) - 7965465..7965704 (+) 240 WP_266466385.1 chaplin -
  OG266_RS35120 (OG266_35095) - 7965910..7966698 (-) 789 WP_266466388.1 hypothetical protein -
  OG266_RS35125 (OG266_35100) - 7966820..7967611 (+) 792 WP_266466391.1 ABC transporter ATP-binding protein -
  OG266_RS35130 (OG266_35105) - 7967705..7968139 (+) 435 WP_371550644.1 NfeD family protein -
  OG266_RS35135 (OG266_35110) - 7968270..7969208 (+) 939 WP_266466395.1 SPFH domain-containing protein -
  OG266_RS35140 (OG266_35115) - 7969278..7969784 (-) 507 WP_266466397.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22953.33 Da        Isoelectric Point: 5.6857

>NTDB_id=646469 OG266_RS35105 WP_266466379.1 7964202..7964843(+) (vraR) [Streptomyces sp. NBC_00554 strain NBC 00554]
MADAIKVLLVDDHQVVRRGLRTFLEIQDDIEVVGEASDGAEGVARAEELKPDVVLMDVRMPGMDGIDALRKLRELTNPAR
VLIVTSFTEKRTVVPALRAGAAGYVYKDVDPEALAGAIRSVHAGHILLQPEVAGVLLSQEEVNSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=646469 OG266_RS35105 WP_266466379.1 7964202..7964843(+) (vraR) [Streptomyces sp. NBC_00554 strain NBC 00554]
GTGGCTGACGCAATCAAGGTGCTGCTTGTCGACGACCACCAAGTGGTCCGCCGGGGCCTGCGCACCTTCCTCGAGATACA
GGACGACATCGAAGTCGTGGGAGAGGCGTCCGACGGCGCCGAAGGAGTCGCCCGCGCCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAGGATGCCGGGCATGGACGGCATCGACGCGCTGCGCAAGCTCCGCGAACTCACCAACCCCGCACGG
GTGTTGATCGTCACCAGCTTCACCGAGAAGCGCACGGTCGTCCCGGCCCTGCGCGCGGGCGCCGCCGGGTACGTGTACAA
GGACGTGGACCCCGAGGCGCTCGCCGGCGCCATCCGTTCCGTGCACGCCGGGCACATCCTGCTCCAGCCCGAGGTGGCGG
GTGTCCTGCTGTCCCAGGAGGAGGTCAACTCGGGTCAGGGGAGAGGAGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCGGACGGCCGCTCCAACCGCGAAATCGCCCGCGCGCTCGTCCTCTCCGAAAAGACCGTCAAGACGCATGT
CTCGAACATCCTGATGAAGCTCGACCTCGCCGACCGTACGCAGGCCGCGCTGTGGGCCGTAAGACACGGTGCGGCCGGGT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.411

97.183

0.441
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404
  letA Legionella pneumophila str. Paris

36.667

98.592

0.362
  letA Legionella pneumophila strain ERS1305867

36.667

98.592

0.362