Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KB229_RS03960 Genome accession   NZ_CP090915
Coordinates   849845..850561 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain 45A5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 844845..855561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KB229_RS03945 (KB229_03945) - 846126..847079 (+) 954 WP_002503805.1 LacI family DNA-binding transcriptional regulator -
  KB229_RS03950 (KB229_03950) - 847339..848811 (+) 1473 WP_001830011.1 sucrose-6-phosphate hydrolase -
  KB229_RS03955 (KB229_03955) - 848818..849777 (+) 960 WP_002485130.1 carbohydrate kinase family protein -
  KB229_RS03960 (KB229_03960) agrA 849845..850561 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  KB229_RS03965 (KB229_03965) agrC 850578..851867 (-) 1290 WP_010959211.1 quorum-sensing sensor histidine kinase AgrC -
  KB229_RS03970 (KB229_03970) agrD 851894..852034 (-) 141 WP_001830021.1 cyclic lactone autoinducer peptide AgrD -
  KB229_RS03975 (KB229_03975) - 852018..852602 (-) 585 WP_234966353.1 accessory gene regulator AgrB -
  KB229_RS03980 (KB229_03980) hld 852919..852996 (+) 78 WP_234966572.1 delta-hemolysin -
  KB229_RS03985 (KB229_03985) - 853431..854162 (-) 732 WP_234966355.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=646436 KB229_RS03960 WP_001829999.1 849845..850561(-) (agrA) [Staphylococcus epidermidis strain 45A5]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=646436 KB229_RS03960 WP_001829999.1 849845..850561(-) (agrA) [Staphylococcus epidermidis strain 45A5]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374