Detailed information NTG0064617

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPYOHK_RS01840
• Genome accession: NZ_AFRY01000001
• Coordinates: 1513847..1514848 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes HKU QMH11M0907901
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1508847..1519848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYOHK_RS01855 (SPYOHK_07420)	thrS	1509017..1510960 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
SPYOHK_RS01850 (SPYOHK_07425)	-	1511382..1512716 (-)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
SPYOHK_RS01845 (SPYOHK_07430)	-	1512718..1513716 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
SPYOHK_RS01840 (SPYOHK_07435)	ccpA	1513847..1514848 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
SPYOHK_RS01835 (SPYOHK_07440)	-	1515022..1516107 (+)	1086	WP_002990707.1	aminopeptidase P family protein	-
SPYOHK_RS01830 (SPYOHK_07445)	-	1516156..1516821 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
SPYOHK_RS01825 (SPYOHK_07450)	-	1516832..1517209 (+)	378	WP_002985686.1	VOC family protein	-
SPYOHK_RS01820 (SPYOHK_07455)	-	1517354..1518280 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
SPYOHK_RS01815 (SPYOHK_07460)	-	1518491..1519174 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=64617 SPYOHK_RS01840 WP_002985680.1 1513847..1514848(-) (ccpA) [Streptococcus pyogenes HKU QMH11M0907901]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=64617 SPYOHK_RS01840 WP_002985680.1 1513847..1514848(-) (ccpA) [Streptococcus pyogenes HKU QMH11M0907901]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559