Detailed information NTG0064345

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: SCV20265_RS25670
• Genome accession: NC_023149
• Coordinates: 5495685..5497022 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa SCV20265
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5490685..5502022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCV20265_RS25645 (SCV20265_5171)	pgeF	5490828..5491556 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
SCV20265_RS25650 (SCV20265_5172)	rluD	5491553..5492515 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
SCV20265_RS25655 (SCV20265_5173)	-	5492661..5493686 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
SCV20265_RS25660 (SCV20265_5174)	-	5493843..5494088 (+)	246	WP_003102591.1	PP0621 family protein	-
SCV20265_RS25665 (SCV20265_5175)	pilS	5494078..5495670 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
SCV20265_RS25670 (SCV20265_5176)	pilR	5495685..5497022 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
SCV20265_RS25675 (SCV20265_5177)	thiO	5497068..5498162 (-)	1095	WP_023122775.1	glycine oxidase ThiO	-
SCV20265_RS25680	-	5498302..5498802 (+)	501	WP_016562346.1	GspH/FimT family pseudopilin	-
SCV20265_RS25685 (SCV20265_5179)	-	5498925..5499413 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
SCV20265_RS25690	pilV	5499423..5499947 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
SCV20265_RS25695 (SCV20265_5180)	-	5499956..5500771 (+)	816	WP_016562347.1	PilW family protein	-
SCV20265_RS25700 (SCV20265_5181)	-	5500768..5501373 (+)	606	WP_003116263.1	PilX N-terminal domain-containing pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=64345 SCV20265_RS25670 WP_003094694.1 5495685..5497022(+) (pilR) [Pseudomonas aeruginosa SCV20265]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=64345 SCV20265_RS25670 WP_003094694.1 5495685..5497022(+) (pilR) [Pseudomonas aeruginosa SCV20265]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384