Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   LZ183_RS08455 Genome accession   NZ_CP090407
Coordinates   1744826..1745800 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain GD4SA159-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1739826..1750800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ183_RS08415 (LZ183_08395) gcvT 1740327..1741418 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  LZ183_RS08420 (LZ183_08400) - 1741577..1742101 (-) 525 WP_001015120.1 shikimate kinase -
  LZ183_RS08425 (LZ183_08405) - 1742091..1742237 (-) 147 WP_001789879.1 hypothetical protein -
  LZ183_RS08430 (LZ183_08410) comGF 1742334..1742831 (-) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  LZ183_RS08435 (LZ183_08415) comGE 1742749..1743048 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  LZ183_RS08440 (LZ183_08420) comGD 1743035..1743481 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  LZ183_RS08445 (LZ183_08425) comGC 1743459..1743770 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  LZ183_RS08450 (LZ183_08430) comGB 1743784..1744854 (-) 1071 WP_000776425.1 competence type IV pilus assembly protein ComGB Machinery gene
  LZ183_RS08455 (LZ183_08435) comGA 1744826..1745800 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  LZ183_RS08460 (LZ183_08440) - 1745852..1746475 (-) 624 WP_113587809.1 MBL fold metallo-hydrolase -
  LZ183_RS08465 (LZ183_08445) - 1746472..1746801 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  LZ183_RS08470 (LZ183_08450) - 1746801..1747787 (-) 987 WP_000161315.1 ROK family glucokinase -
  LZ183_RS08475 (LZ183_08455) - 1747784..1747987 (-) 204 WP_000087559.1 YqgQ family protein -
  LZ183_RS08480 (LZ183_08460) - 1747968..1749431 (-) 1464 WP_001017856.1 rhomboid family intramembrane serine protease -
  LZ183_RS08485 (LZ183_08465) - 1749443..1749982 (-) 540 WP_000164554.1 5-formyltetrahydrofolate cyclo-ligase -
  LZ183_RS08490 (LZ183_08470) rpmG 1750191..1750340 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=642121 LZ183_RS08455 WP_000697220.1 1744826..1745800(-) (comGA) [Staphylococcus aureus strain GD4SA159-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=642121 LZ183_RS08455 WP_000697220.1 1744826..1745800(-) (comGA) [Staphylococcus aureus strain GD4SA159-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1