Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   LY388_RS10440 Genome accession   NZ_CP090387
Coordinates   1066167..1068410 (+) Length   747 a.a.
NCBI ID   WP_265100986.1    Uniprot ID   -
Organism   Vibrio cholerae strain GXFL1-4     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1061167..1073410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LY388_RS10415 (LY388_10415) - 1061630..1062205 (-) 576 WP_000999601.1 PilZ domain-containing protein -
  LY388_RS10420 (LY388_10420) lolC 1062381..1063589 (+) 1209 WP_199358064.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  LY388_RS10425 (LY388_10425) lolD 1063582..1064268 (+) 687 WP_001061289.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  LY388_RS10430 (LY388_10430) lolE 1064269..1065513 (+) 1245 WP_000493013.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  LY388_RS10435 (LY388_10435) - 1065628..1066158 (-) 531 WP_001881633.1 DUF2062 domain-containing protein -
  LY388_RS10440 (LY388_10440) comEC 1066167..1068410 (+) 2244 WP_265100986.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LY388_RS10445 (LY388_10445) msbA 1068441..1070189 (+) 1749 WP_000052155.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  LY388_RS10450 (LY388_10450) lpxK 1070192..1071199 (+) 1008 WP_234116164.1 tetraacyldisaccharide 4'-kinase -
  LY388_RS10455 (LY388_10455) - 1071180..1071359 (+) 180 WP_000350068.1 Trm112 family protein -
  LY388_RS10460 (LY388_10460) kdsB 1071359..1072117 (+) 759 WP_000011329.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 84481.68 Da        Isoelectric Point: 7.9639

>NTDB_id=641925 LY388_RS10440 WP_265100986.1 1066167..1068410(+) (comEC) [Vibrio cholerae strain GXFL1-4]
MTLLSNYWSLISFSITVLSAPYWPWMPSWGWAWLCLIVMVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGP
DIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTRPRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYM
AQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHTSPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHI
GIAFSVGYFLGLGMMRLHAQLLWSPFVCGALLAVLYAWLAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLGAVL
LWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKALLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVI
VPALFWGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQFADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMMG
LWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDTGSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDW
QGLAERWQPNWIRASQLGAEFMPCIRGESWQWQSLHFTVLWPPQAVSRAYNQHSCVIRMTDTQSKHSVLLSGDVTAMGEW
LLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLAIASVAKDNRWNLPNPQVVARYQAQQVEWLDTGQAGQISLFFY
PEQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=641925 LY388_RS10440 WP_265100986.1 1066167..1068410(+) (comEC) [Vibrio cholerae strain GXFL1-4]
ATGACTCTCTTGTCGAATTACTGGTCTCTCATTTCTTTTTCGATCACCGTGCTGTCTGCCCCTTATTGGCCTTGGATGCC
GAGTTGGGGTTGGGCTTGGTTATGCCTTATTGTTATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCT
TCGTGGCTGCCATACTAACCATTGTGCTACAGGGCAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCG
GATATTATCATAAAAGGCCGTGTTGACAGCTTTTTTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGA
AGTGAATGGACAAACCTTAAACAAAATGACTCGCCCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACC
GCGTCGAATTTTCGGTAACTCTCAAGCCGATAGTGGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATG
GCGCAATCTGTCGTCGCACGGGCGGTCGTAAAACCTGACACCGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAG
TTTGTTTTTTGAGCTGGAACAATTAACGCATACCAGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAA
AAGGTATTGATGAGCAAGAGTGGCAAGCCTTACGCAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTGCACATT
GGTATCGCTTTTAGCGTGGGTTATTTTCTCGGGCTCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGT
GTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGGCTGGCTGGATTTACGTTGCCTACTCAGCGTGCATTGATTATGTGCT
TACTCAATGTGGCGTTGATCATGTTGGCTTTTCCTCTTTCCGCGCTCAAGCGGATTCTACTCACCTTGGGCGCGGTCTTG
CTTTGGTCGCCATTCGCCTCACTTTCAAACAGTTTCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGC
CAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCTCTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCA
CGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGCAGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATT
GTCCCAGCTTTGTTTTGGGGTCTATTACTCATGGTGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTG
GACGTTTTTACCGCTCGATTGGGCTTTGCAGTTTGCCGATGTAGGCTGGTGGGTGGTACCCAGCAAAGTACAAGGTGTGG
TCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCGATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATGGGC
TTATGGTGGTGGTTTCCCTCTCTCACTCCACTTTGGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGAT
TGAGCAAGATGAGCGAGCAATTGTCTACGATACAGGCAGCAGTTGGCCGGGAGGCAGTTATGTGCAAAGCGTGATTGAGC
CTATTCTCCAACAGCGAGGGCTACGCCAAGTCGATGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGG
CAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGATTCGTGCCAGCCAACTCGGGGCAGAGTTTATGCCTTGTATCCGTGG
TGAAAGCTGGCAGTGGCAATCTCTCCATTTTACGGTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATT
CGTGTGTGATTCGTATGACTGATACTCAGTCTAAGCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGG
CTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTGAGGTGATGATCGTGCCGCACCACGGCAGTAAAACATCGTCCACCGC
AGAGTTTATTGCCCAAGTGAATCCCAAACTTGCGATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGC
AAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGAGTGGCTAGATACTGGACAAGCTGGGCAAATTAGCCTCTTTTTCTAT
CCAGAACAGCTGGATTGGTTTACCCAGCGTAGCCTTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGA
ATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(21-173)

Competence protein (Competence)

(208-464)

Metallo-beta-lactamase superfamily (Lactamase_B)

(499-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

98.661

100

0.987
  comEC Vibrio parahaemolyticus RIMD 2210633

41.347

100

0.419
  comEC Vibrio campbellii strain DS40M4

41.114

100

0.415