Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FH104_RS08945 Genome accession   NZ_CP090014
Coordinates   1804340..1804969 (+) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis strain acrlk     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1799340..1809969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FH104_RS08915 (FH104_08895) - 1799605..1800594 (-) 990 WP_070813217.1 FUSC family protein -
  FH104_RS08920 (FH104_08900) map 1800768..1801520 (+) 753 WP_049382583.1 type I methionyl aminopeptidase -
  FH104_RS08925 (FH104_08905) - 1801775..1801867 (-) 93 Protein_1743 hypothetical protein -
  FH104_RS08930 (FH104_08910) - 1802198..1802584 (+) 387 WP_070813218.1 hypothetical protein -
  FH104_RS08935 (FH104_08915) liaF 1802606..1803307 (+) 702 WP_017175229.1 cell wall-active antibiotics response protein LiaF -
  FH104_RS08940 (FH104_08920) vraS 1803304..1804338 (+) 1035 WP_017175228.1 sensor histidine kinase Regulator
  FH104_RS08945 (FH104_08925) vraR 1804340..1804969 (+) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  FH104_RS08950 (FH104_08930) - 1805048..1806250 (-) 1203 WP_061815718.1 YihY/virulence factor BrkB family protein -
  FH104_RS08955 (FH104_08935) - 1806342..1806623 (-) 282 WP_002450075.1 hypothetical protein -
  FH104_RS08960 (FH104_08940) - 1806629..1807093 (-) 465 WP_070813219.1 low molecular weight protein-tyrosine-phosphatase -
  FH104_RS08965 (FH104_08945) - 1807235..1807441 (+) 207 WP_002450082.1 DUF1128 domain-containing protein -
  FH104_RS08970 (FH104_08950) - 1807453..1808700 (+) 1248 WP_070813220.1 aminopeptidase -
  FH104_RS08975 (FH104_08955) - 1808733..1809266 (+) 534 WP_070813221.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=640218 FH104_RS08945 WP_002450048.1 1804340..1804969(+) (vraR) [Staphylococcus hominis strain acrlk]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=640218 FH104_RS08945 WP_002450048.1 1804340..1804969(+) (vraR) [Staphylococcus hominis strain acrlk]
ATGACGATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGAGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCATATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGAGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCCAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTCGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378