Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   LV497_RS09440 Genome accession   NZ_CP090007
Coordinates   2042309..2043016 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain SALI-10     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2037309..2048016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS09415 (LV497_09415) - 2038068..2038835 (-) 768 WP_060775856.1 amino acid ABC transporter ATP-binding protein -
  LV497_RS09420 (LV497_09420) - 2039021..2039671 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  LV497_RS09425 (LV497_09425) - 2039683..2040381 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  LV497_RS09430 (LV497_09430) - 2040399..2041232 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  LV497_RS09435 (LV497_09435) - 2041242..2042009 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  LV497_RS09440 (LV497_09440) vicR 2042309..2043016 (+) 708 WP_002884978.1 response regulator YycF Regulator
  LV497_RS09445 (LV497_09445) vicK 2043009..2044352 (+) 1344 WP_038675887.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LV497_RS09450 (LV497_09450) vicX 2044358..2045167 (+) 810 WP_126405093.1 MBL fold metallo-hydrolase Regulator
  LV497_RS09455 (LV497_09455) - 2045226..2045585 (+) 360 WP_037611660.1 YbaN family protein -
  LV497_RS09460 (LV497_09460) - 2045637..2046851 (-) 1215 WP_070577164.1 aminoacyltransferase -
  LV497_RS09465 (LV497_09465) yidA 2046853..2047662 (-) 810 WP_002890845.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=640153 LV497_RS09440 WP_002884978.1 2042309..2043016(+) (vicR) [Streptococcus salivarius strain SALI-10]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=640153 LV497_RS09440 WP_002884978.1 2042309..2043016(+) (vicR) [Streptococcus salivarius strain SALI-10]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCGATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387