Detailed information NTG0639441

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: LXA49_RS09740
• Genome accession: NZ_CP089949
• Coordinates: 1893023..1894033 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain SN75752
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1888023..1899033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA49_RS09715 (LXA49_09700)	-	1889188..1889482 (-)	295	Protein_1926	hypothetical protein	-
LXA49_RS09720 (LXA49_09705)	-	1889644..1890096 (+)	453	WP_054368216.1	universal stress protein	-
LXA49_RS09725 (LXA49_09710)	-	1890131..1891519 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
LXA49_RS09730 (LXA49_09715)	-	1891585..1892547 (+)	963	WP_001124786.1	asparaginase	-
LXA49_RS09735 (LXA49_09720)	-	1892576..1892959 (-)	384	WP_001092022.1	hypothetical protein	-
LXA49_RS09740 (LXA49_09725)	ccpA	1893023..1894033 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
LXA49_RS09745 (LXA49_09730)	-	1894458..1895057 (-)	600	WP_000866703.1	response regulator transcription factor	-
LXA49_RS09750 (LXA49_09735)	-	1895058..1896155 (-)	1098	WP_000893503.1	sensor histidine kinase	-
LXA49_RS09755 (LXA49_09740)	-	1896155..1896892 (-)	738	WP_000832916.1	ABC transporter permease	-
LXA49_RS09760 (LXA49_09745)	-	1896894..1897778 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
LXA49_RS09765 (LXA49_09750)	-	1897765..1897959 (-)	195	WP_000715302.1	hypothetical protein	-
LXA49_RS09770 (LXA49_09755)	-	1897956..1898162 (-)	207	Protein_1937	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=639441 LXA49_RS09740 WP_000990607.1 1893023..1894033(-) (ccpA) [Streptococcus pneumoniae strain SN75752]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=639441 LXA49_RS09740 WP_000990607.1 1893023..1894033(-) (ccpA) [Streptococcus pneumoniae strain SN75752]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568