Detailed information NTG0639428

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: LXA49_RS09125
• Genome accession: NZ_CP089949
• Coordinates: 1785190..1786257 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain SN75752
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1780190..1791257

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA49_RS09100 (LXA49_09090)	treR	1780377..1781087 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
LXA49_RS09105 (LXA49_09095)	-	1781120..1781923 (-)	804	WP_000157672.1	ATP-binding cassette domain-containing protein	-
LXA49_RS09110 (LXA49_09100)	-	1781936..1782813 (-)	878	Protein_1828	ABC transporter permease	-
LXA49_RS09115 (LXA49_09105)	-	1782825..1783762 (-)	938	Protein_1829	ABC transporter substrate-binding protein	-
LXA49_RS09120 (LXA49_09110)	amiF	1784253..1785179 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
LXA49_RS09125 (LXA49_09115)	amiE	1785190..1786257 (-)	1068	WP_000159554.1	oligopeptide/dipeptide ABC transporter ATP-binding protein	Regulator
LXA49_RS09130 (LXA49_09120)	amiD	1786266..1787192 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
LXA49_RS09135 (LXA49_09125)	amiC	1787192..1788688 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
LXA49_RS09140 (LXA49_09130)	amiA3	1788755..1790734 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=639428 LXA49_RS09125 WP_000159554.1 1785190..1786257(-) (amiE) [Streptococcus pneumoniae strain SN75752]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=639428 LXA49_RS09125 WP_000159554.1 1785190..1786257(-) (amiE) [Streptococcus pneumoniae strain SN75752]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541