Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA3   Type   Regulator
Locus tag   LXA49_RS02080 Genome accession   NZ_CP089949
Coordinates   381299..383281 (+) Length   660 a.a.
NCBI ID   WP_000842576.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN75752     
Function   binding to XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 371731..381121 381299..383281 flank 178


Gene organization within MGE regions


Location: 371731..383281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS02030 (LXA49_02025) - 371731..372210 (+) 480 WP_000578428.1 glycosyltransferase -
  LXA49_RS02035 (LXA49_02030) - 372452..373549 (+) 1098 WP_000697445.1 glycosyltransferase family 1 protein -
  LXA49_RS02040 (LXA49_02035) - 373577..374230 (+) 654 WP_001813487.1 DUF1919 domain-containing protein -
  LXA49_RS02045 (LXA49_02040) - 374227..374949 (+) 723 WP_000612419.1 glycosyltransferase -
  LXA49_RS02050 (LXA49_02045) - 374946..376118 (+) 1173 WP_001222996.1 O-antigen ligase family protein -
  LXA49_RS02055 (LXA49_02050) - 376108..376608 (+) 501 WP_013315037.1 acyltransferase -
  LXA49_RS02060 (LXA49_02055) - 376618..377805 (+) 1188 WP_001028552.1 CDP-glycerol glycerophosphotransferase family protein -
  LXA49_RS02065 (LXA49_02060) - 377762..379225 (+) 1464 WP_013315038.1 oligosaccharide flippase family protein -
  LXA49_RS02070 (LXA49_02065) tagD 379339..379731 (+) 393 WP_000832258.1 glycerol-3-phosphate cytidylyltransferase -
  LXA49_RS02075 (LXA49_02070) - 380093..381121 (+) 1029 WP_000170108.1 acyltransferase -
  LXA49_RS02080 (LXA49_02075) amiA3 381299..383281 (+) 1983 WP_000842576.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 73036.67 Da        Isoelectric Point: 4.7548

>NTDB_id=639392 LXA49_RS02080 WP_000842576.1 381299..383281(+) (amiA3) [Streptococcus pneumoniae strain SN75752]
MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVIIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEAT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=639392 LXA49_RS02080 WP_000842576.1 381299..383281(+) (amiA3) [Streptococcus pneumoniae strain SN75752]
ATGAAAAGTTCAAAACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGCACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTTTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATTTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATACACATCTAAG
ACCAGCGACGAACAAAAGGCATCGACTAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCCTTTGGTTTTGA
TCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCCTTACA
AGCAGAAGGTGTGACTTTCCCAATTCATTTGGATATGCCAGTTGACCAGACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCTGATAATGTCATTATTGATATCCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGCGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGGCTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATCTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGCACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(77-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA3 Streptococcus thermophilus LMD-9

58.245

100

0.583
  amiA3 Streptococcus thermophilus LMG 18311

57.943

100

0.58
  amiA Streptococcus salivarius strain HSISS4

57.791

100

0.579