Detailed information NTG0639358

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: LXA46_RS09505
• Genome accession: NZ_CP089948
• Coordinates: 1895123..1896133 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae TIGR4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1890123..1901133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA46_RS09480 (LXA46_09465)	-	1891108..1891402 (-)	295	Protein_1885	hypothetical protein	-
LXA46_RS09485 (LXA46_09470)	-	1891564..1892016 (+)	453	WP_000079148.1	universal stress protein	-
LXA46_RS09490 (LXA46_09475)	-	1892051..1893439 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
LXA46_RS09495 (LXA46_09480)	-	1893505..1894467 (+)	963	WP_001124777.1	asparaginase	-
LXA46_RS09500 (LXA46_09485)	-	1894496..1895059 (-)	564	WP_001092024.1	hypothetical protein	-
LXA46_RS09505 (LXA46_09490)	ccpA	1895123..1896133 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
LXA46_RS09510 (LXA46_09495)	-	1896558..1897157 (-)	600	WP_000866703.1	response regulator transcription factor	-
LXA46_RS09515 (LXA46_09500)	-	1897158..1898255 (-)	1098	WP_000893503.1	sensor histidine kinase	-
LXA46_RS09520 (LXA46_09505)	-	1898255..1898992 (-)	738	WP_000832915.1	ABC transporter permease	-
LXA46_RS09525 (LXA46_09510)	-	1898994..1899878 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
LXA46_RS09530 (LXA46_09515)	-	1899865..1900059 (-)	195	WP_000820189.1	hypothetical protein	-
LXA46_RS09535 (LXA46_09520)	-	1900056..1900262 (-)	207	Protein_1896	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=639358 LXA46_RS09505 WP_000990607.1 1895123..1896133(-) (ccpA) [Streptococcus pneumoniae TIGR4]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=639358 LXA46_RS09505 WP_000990607.1 1895123..1896133(-) (ccpA) [Streptococcus pneumoniae TIGR4]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568