Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OCL07_RS09855 Genome accession   NZ_CP106954
Coordinates   1999745..2000401 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain T43     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994745..2005401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCL07_RS09820 (OCL07_09790) dcyD 1995625..1996611 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  OCL07_RS09825 (OCL07_09795) tcyL 1996626..1997294 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  OCL07_RS09830 (OCL07_09800) tcyN 1997291..1998043 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  OCL07_RS09835 (OCL07_09805) sdiA 1998273..1998995 (+) 723 WP_032200101.1 transcriptional regulator SdiA -
  OCL07_RS09840 (OCL07_09810) yecF 1999062..1999286 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  OCL07_RS09845 (OCL07_09815) yecU 1999273..1999449 (-) 177 WP_001307856.1 protein YecU -
  OCL07_RS09850 - 1999532..1999603 (-) 72 Protein_1924 transcriptional regulator -
  OCL07_RS09855 (OCL07_09820) letA 1999745..2000401 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  OCL07_RS09860 (OCL07_09825) uvrC 2000398..2002230 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  OCL07_RS09865 (OCL07_09830) pgsA 2002287..2002835 (+) 549 WP_032200177.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  OCL07_RS09885 (OCL07_09850) yecA 2003485..2004150 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=638868 OCL07_RS09855 WP_000611335.1 1999745..2000401(+) (letA) [Escherichia coli strain T43]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=638868 OCL07_RS09855 WP_000611335.1 1999745..2000401(+) (letA) [Escherichia coli strain T43]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486