Detailed information NTG0637592

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: OCL43_RS10280
• Genome accession: NZ_CP106801
• Coordinates: 1952263..1953489 (-)
• Length: 408 a.a.
• NCBI ID: WP_047920901.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain 10744
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1947263..1958489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OCL43_RS10270 (OCL43_10270)	-	1949036..1949320 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
OCL43_RS10275 (OCL43_10275)	yccS	1949996..1952146 (-)	2151	WP_003697785.1	YccS family putative transporter	-
OCL43_RS10280 (OCL43_10280)	pilU	1952263..1953489 (-)	1227	WP_047920901.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
OCL43_RS10285 (OCL43_10285)	pilT	1953653..1954696 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
OCL43_RS10290 (OCL43_10290)	-	1954816..1955502 (+)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
OCL43_RS10295 (OCL43_10295)	-	1955502..1955909 (+)	408	WP_235220100.1	RNA-binding protein	-
OCL43_RS10300 (OCL43_10300)	proC	1955958..1956749 (+)	792	WP_260245430.1	pyrroline-5-carboxylate reductase	-
OCL43_RS10305 (OCL43_10305)	dksA	1956898..1957314 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45670.27 Da
• Isoelectric Point: 7.0921

>NTDB_id=637592 OCL43_RS10280 WP_047920901.1 1952263..1953489(-) (pilU) [Neisseria gonorrhoeae strain 10744]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=637592 OCL43_RS10280 WP_047920901.1 1952263..1953489(-) (pilU) [Neisseria gonorrhoeae strain 10744]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCAGGAATTGGGCTTACCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGATCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	45.225	87.255	0.395
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387